Pediatric papillary thyroid carcinoma (PPTC) is clinically distinct from adult-onset disease.
Although there are higher rates of metastasis and recurrence in PPTC, prognosis remains …

Background Pediatric papillary thyroid carcinoma (PTC) is clinically and biologically distinct
from adult PTC. We sequenced a cohort of clinically annotated pediatric PTC cases enriched …

Pediatric papillary thyroid carcinomas (pPTCs) are often indolent tumors with excellent long-
term outcome, although subsets of cases are clinically troublesome and recur. Although it is …

Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with
increasing incidence. Pediatric PTCs have distinct clinical and pathological features and …

Context Fusion oncogenes, especially those involving RET or NTRK, are known drivers of
papillary thyroid cancer (PTC). They are prevalent in pediatric patients and correlate with …

PURPOSE In 2014, data from a comprehensive multiplatform analysis of 496 adult papillary
thyroid cancer samples reported by The Cancer Genome Atlas project suggested that …

BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma
(PTC), has been recently reported in children. METHODS The histopathology of 28 …

BACKGROUND Molecular characterization in pediatric papillary thyroid cancer (PTC),
distinct from adult PTC, is important for developing molecularly targeted therapies for …

Objective PTC-specific analysis identified novel fusions involving RET, BRAF, NTRK1,
NTRK3, AGK and ALK genes in adults and pediatric PTCs. Although many novel fusions are …

Simple Summary Papillary thyroid carcinoma (PTC) in pediatric patients shows different
characteristics compared with PTC in adults. In this large mono-institutional cohort of …