Spatial transcriptomics: technical aspects of recent developments and their applications in neuroscience and cancer research
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …
of the spatial localization of transcripts and related analyses in various applications for …
Spatial transcriptomic technologies
Spatial transcriptomic technologies enable measurement of expression levels of genes
systematically throughout tissue space, deepening our understanding of cellular …
systematically throughout tissue space, deepening our understanding of cellular …
Spatial transcriptomics in development and disease
The proper functioning of diverse biological systems depends on the spatial organization of
their cells, a critical factor for biological processes like shaping intricate tissue functions and …
their cells, a critical factor for biological processes like shaping intricate tissue functions and …
[HTML][HTML] Spatial transcriptomics: Technologies, applications and experimental considerations
The diverse cell types of an organ have a highly structured organization to enable their
efficient and correct function. To fully appreciate gene functions in a given cell type, one …
efficient and correct function. To fully appreciate gene functions in a given cell type, one …
Analysis and visualization of spatial transcriptomic data
Human and animal tissues consist of heterogeneous cell types that organize and interact in
highly structured manners. Bulk and single-cell sequencing technologies remove cells from …
highly structured manners. Bulk and single-cell sequencing technologies remove cells from …
Spatial transcriptomics in neuroscience
N Jung, TK Kim - Experimental & Molecular Medicine, 2023 - nature.com
The brain is one of the most complex living tissue types and is composed of an exceptional
diversity of cell types displaying unique functional connectivity. Single-cell RNA sequencing …
diversity of cell types displaying unique functional connectivity. Single-cell RNA sequencing …
[HTML][HTML] A guidebook of spatial transcriptomic technologies, data resources and analysis approaches
L Yue, F Liu, J Hu, P Yang, Y Wang, J Dong… - Computational and …, 2023 - Elsevier
Advances in transcriptomic technologies have deepened our understanding of the cellular
gene expression programs of multicellular organisms and provided a theoretical basis for …
gene expression programs of multicellular organisms and provided a theoretical basis for …
Advances in spatial transcriptomics and related data analysis strategies
J Du, YC Yang, ZJ An, MH Zhang, XH Fu… - Journal of Translational …, 2023 - Springer
Spatial transcriptomics technologies developed in recent years can provide various
information including tissue heterogeneity, which is fundamental in biological and medical …
information including tissue heterogeneity, which is fundamental in biological and medical …
Computational approaches and challenges in spatial transcriptomics
S Fang, B Chen, Y Zhang, H Sun, L Liu… - Genomics …, 2023 - academic.oup.com
The development of spatial transcriptomics (ST) technologies has transformed genetic
research from a single-cell data level to a two-dimensional spatial coordinate system and …
research from a single-cell data level to a two-dimensional spatial coordinate system and …
SpatialDB: a database for spatially resolved transcriptomes
Z Fan, R Chen, X Chen - Nucleic acids research, 2020 - academic.oup.com
Spatially resolved transcriptomic techniques allow the characterization of spatial
organization of cells in tissues, which revolutionize the studies of tissue function and disease …
organization of cells in tissues, which revolutionize the studies of tissue function and disease …