Somatostatin (SST), cortistatin (CORT), and their receptors (SSTR1-5/sst5TMD4-TMD5)
comprise a multifactorial hormonal system involved in the regulation of numerous …

BACKGROUND: Prostate cancer (PCa) is the most common type of cancer among men in
Western countries. Despite numerous therapeutic options, few treatments are available for …

Background Prostate cancer (PCa) is a highly prevalent neoplasia that is strongly influenced
by the endocrine system. Somatostatin (SST) and its five receptors (sst1‐5 encoded by …

Prostate cancer (PC) is one of the most frequently diagnosed cancers and a leading cause
of cancer-related deaths in Western society. Current PC therapies prevalently target the …

Somatostatin receptor subtype 2 (SSTR2) is the most frequently expressed SSTR subtype in
normal human tissues. SSTR2 expression is differentially regulated in various tumor types …

Although some evidence supports the antitumoral effects of somatostatin (SRIF) and related
agonists, the available data in prostate cancer (PCa) model systems and clinical studies are …

Neuroendocrine cells have been found in all the stages of prostate cancer, but their clinical
significance is not completely understood. Neuroendocrine cells are androgen receptor-and …

Cancer cell metabolism responsive to androgen deprivation therapy (ADT) may be involved
in the development and progression of prostate cancer and the ultimate failure of androgen …

The aim of the study is to examine the tissue expression and localization of the somatostatin
receptors (SSTRs) in prostate cancer (PCa) with neuroendocrine (NE) differentiation. The …

Objective: The aim was to examine the expression and localization of the five somatostatin
receptors (termed SSTR1–5) in radical prostatectomies (RPs) from patients with prostatic …