A new structure–activity relationship for cyanine dyes to improve photostability and fluorescence properties for live cell imaging

C Schwechheimer, F Rönicke, U Schepers… - Chemical …, 2018 - pubs.rsc.org
A new set of cyanine-indole dyes was synthesized, characterized by optical and cytotoxic
properties and subsequently applied for live cell imaging. Furthermore, these dyes were …

Synthesis and evaluation of cyanine–styryl dyes with enhanced photostability for fluorescent DNA staining

PR Bohländer, HA Wagenknecht - Organic & Biomolecular Chemistry, 2013 - pubs.rsc.org
Synthesis and evaluation of cyanine–styryl dyes with enhanced photostability for fluorescent
DNA staining - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C3OB41717D …

Non-cytotoxic photostable monomethine cyanine platforms: Combined paradigm of nucleic acid staining and in vivo imaging

A Kurutos, T Ilic-Tomic, FS Kamounah… - … of Photochemistry and …, 2020 - Elsevier
Cyanine based chemosensing platforms have successfully been employed over the past
couple of decades in various fields of biomolecular sciences. Still a substantial number of …

Synthesis and optical properties of cyanine dyes as fluorescent DNA base substitutions for live cell imaging

C Holzhauser, S Berndl, F Menacher, M Breunig… - 2010 - Wiley Online Library
The chromophore of thiazole orange (TO) and its derivative TO3 were incorporated
synthetically as base surrogates into oligonucleotides using automated phosphoramidite …

Impact of Substituents in Tumor Uptake and Fluorescence Imaging Ability of Near‐Infrared Cyanine‐like Dyes

NJ Patel, E Manivannan, P Joshi… - Photochemistry and …, 2015 - Wiley Online Library
This report presents a simple strategy to introduce various functionalities in a cyanine dye
(bis‐indole‐N‐butylsulfonate‐polymethine bearing a fused cyclic chloro‐cyclohexene ring …

A bright red fluorescent cyanine dye for live-cell nucleic acid imaging, with high photostability and a large Stokes shift

S Zhang, J Fan, Z Li, N Hao, J Cao, T Wu… - Journal of Materials …, 2014 - pubs.rsc.org
Many probes for nucleic acids are available, but few of them satisfy multiple criteria,
particularly high photostability to endure laser scanning. We report a cyanine dye TO3-CN …

Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn‐On DNA Probes

K Uno, T Sasaki, N Sugimoto, H Ito… - Chemistry–An Asian …, 2017 - Wiley Online Library
Unsymmetrical cyanine dyes, such as thiazole orange, are useful for the detection of nucleic
acids with fluorescence because they dramatically enhance the fluorescence upon binding …

Structure property analysis of pentamethine indocyanine dyes: identification of a new dye for life science applications

O Mader, K Reiner, HJ Egelhaaf, R Fischer… - Bioconjugate …, 2004 - ACS Publications
A collection of nine pentamethine indocyanine dyes was synthesized, and the photophysical
characteristics relevant to applications in cell biology and single molecule detection were …

Small molecular cyanine dyes for phototheranostics

J Zhang, W Wang, J Shao, J Chen, X Dong - Coordination Chemistry …, 2024 - Elsevier
Cyanine dyes, one of the most important classes of organic fluorophores, have recently
attracted more and more attention for their applications in fluorescence imaging, tumor …

Experimental and DFT studies: novel structural modifications greatly enhance the solvent sensitivity of live cell imaging dyes

A Toutchkine, WG Han, M Ullmann, T Liu… - The Journal of …, 2007 - ACS Publications
Structural modifications of previously reported merocyanine dyes (Toutchkine, A.; Kraynov,
V.; Hahn, KJ Am. Chem. Soc. 2003, 125, 4132− 4145) were found to greatly enhance the …