Worldwide prevalence of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis

B Melosky, K Kambartel, M Haentschel… - Molecular Diagnosis & …, 2022 - Springer
Background Identification of variable epidermal growth factor receptor (EGFR) gene
mutations in non-small cell lung cancer (NSCLC) is important for the selection of appropriate …

[HTML][HTML] The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis

YL Zhang, JQ Yuan, KF Wang, XH Fu, XR Han… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Objectives Estimate the epidermal growth factor receptor (EGFR) mutation prevalence in all
non-small cell lung cancer (NSCLC) patients and patient subgroups. Results A total of 456 …

[HTML][HTML] Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer

PT Harrison, S Vyse, PH Huang - Seminars in cancer biology, 2020 - Elsevier
Epidermal growth factor receptor (EGFR) mutations are the second most common oncogenic
driver event in non-small cell lung cancer (NSCLC). Classical activating mutations (exon 19 …

Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy

Y Kobayashi, T Mitsudomi - Cancer science, 2016 - Wiley Online Library
Somatic mutations in the epidermal growth factor receptor (EGFR) gene are present in
approximately 20%(in Caucasians) to 40%(in East Asians) of adenocarcinomas of the lung …

Concurrent driver gene mutations as negative predictive factors in epidermal growth factor receptor-positive non-small cell lung cancer

M Chen, Y Xu, J Zhao, W Zhong, L Zhang, Y Bi… - …, 2019 - thelancet.com
Abstract Background Tyrosine kinase inhibitors (TKIs) are clinically effective in non-small
cell lung cancer (NSCLC) patients harbouring epidermal growth factor receptor (EGFR) …

[HTML][HTML] Epidermal growth factor receptor mutations and their correlation with gefitinib therapy in patients with non-small cell lung cancer: a meta-analysis based on …

YL Wu, WZ Zhong, LY Li, XT Zhang, L Zhang… - Journal of Thoracic …, 2007 - Elsevier
Background Convincing data on epidermal growth factor receptor (EGFR) mutations in
Chinese patients with non-small-cell lung cancer (NSCLC) remain limited. We investigated …

The significance of epidermal growth factor receptor uncommon mutations in non-small cell lung cancer: A systematic review and critical appraisal

V Gristina, U Malapelle, A Galvano, P Pisapia… - Cancer Treatment …, 2020 - Elsevier
Uncommon epidermal growth factor receptor (EGFR) mutations collectively account for 10%
of EGFR mutations, harboring heterogeneous molecular alterations within exons 18–21 with …

Effectiveness of tyrosine kinase inhibitors on “uncommon” epidermal growth factor receptor mutations of unknown clinical significance in non–small cell lung cancer

JY Wu, CJ Yu, YC Chang, CH Yang, JY Shih… - Clinical cancer …, 2011 - AACR
Purpose: Clinical features of epidermal growth factor receptor (EGFR) mutations, L858R,
deletions in exon 19, T790M, and insertions in exon 20, in non–small cell lung cancer …

Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma

N Girard, CS Sima, DM Jackman… - European …, 2012 - Eur Respiratory Soc
Epidermal growth factor receptor (EGFR) tumour genotyping is crucial to guide treatment
decisions regarding the use of EGFR tyrosine kinase inhibitors in nonsmall cell lung cancer …

Molecular epidemiology of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology–mainland China subset analysis …

Y Shi, J Li, S Zhang, M Wang, S Yang, N Li, G Wu… - PloS one, 2015 - journals.plos.org
Epidermal growth factor receptor (EGFR) mutations are the strongest response predictors to
EGFR tyrosine kinase inhibitors (TKI) therapy, but knowledge of the EGFR mutation …