Purpose Diagnosing early diabetic peripheral neuropathy remains a challenge due to
deficiencies in currently advocated end points. The cornea is densely innervated with small …

Accurate detection and quantification of human diabetic peripheral neuropathy are important
to define at-risk patients, anticipate deterioration, and assess new therapies. Easily …

Objective Screening for diabetic peripheral neuropathy (DPN) is essential for early detection
and timely intervention. Quantitative assessment of small nerve fiber damage is key to the …

Aims/hypothesis The accurate detection, characterization and quantification of human
diabetic neuropathy are important to define at risk patients, anticipate deterioration, and …

Distal symmetric polyneuropathy (DPN), particularly chronic sensorimotor DPN, represents
one of the most frequent complications of diabetes, affecting 50% of diabetic patients and …

OBJECTIVE The accurate quantification of human diabetic neuropathy is important to define
at-risk patients, anticipate deterioration, and assess new therapies. RESEARCH DESIGN …

Introduction Diabetic neuropathy can be diagnosed and assessed using a number of
techniques including corneal confocal microscopy (CCM). Research design and methods …

Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

Corneal confocal microscopy (CCM) is a noninvasive method for the study of human cornea
in vivo. It has increasingly been used to assess the morphology of the sub-basal corneal …

Diabet. Med. 28, 1261–1267 (2011) Abstract Aim We have assessed whether corneal
confocal microscopy can be used to detect alterations in nerve morphology following an …