Because of its availability, ease of collection, and correlation with physiology and pathology,
urine is an attractive source for clinical proteomics/peptidomics. However, the lack of …

Urinary peptidomics focuses on endogenous urinary peptide content. Many studies now
show the usefulness of this approach for the discovery and validation of biomarkers in …

Purpose: Human urine is an ideal candidate for use in clinical diagnostics. It is easily
available, as untrained personnel can collect it. It correlates well with the pathophysiology of …

Owing to its availability, ease of collection, and correlation with pathophysiology of diseases,
urine is an attractive source for clinical proteomics. However, many proteomic studies have …

Urine proteins can serve as viable biomarkers for diagnosing and monitoring various
diseases. A comprehensive urine proteome database, generated from a variety of urine …

Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

A myriad of proteins and peptides can be identified in normal human urine. These are
derived from a variety of sources including glomerular filtration of blood plasma, cell …

A limitation of proteomic methods with respect to their clinical applicability is the lack of
possibilities to directly deduce the amount of a protein or peptide from a particular mass …

Biomarkers are measurable changes associated with the disease. Urine can reflect the
changes of the body while blood is under control of the homeostatic mechanisms; thus, urine …

Urine is an important source of biomarkers. A single proteomics assay can identify hundreds
of differentially expressed proteins between disease and control samples; however, the …