Targeting immunogenic cell death in cancer

A Ahmed, SWG Tait - Molecular oncology, 2020 - Wiley Online Library
Immunogenic cell death (ICD) is a type of cancer cell death triggered by certain
chemotherapeutic drugs, oncolytic viruses, physicochemical therapies, photodynamic …

Immunogenic cell death in cancer therapy: Present and emerging inducers

J Zhou, G Wang, Y Chen, H Wang… - Journal of cellular and …, 2019 - Wiley Online Library
In the tumour microenvironment (TME), immunogenic cell death (ICD) plays a major role in
stimulating the dysfunctional antitumour immune system. Chronic exposure of damage …

[HTML][HTML] Realizing the clinical potential of immunogenic cell death in cancer chemotherapy and radiotherapy

BL Rapoport, R Anderson - International journal of molecular sciences, 2019 - mdpi.com
Immunogenic cell death (ICD), which is triggered by exposure of tumor cells to a limited
range of anticancer drugs, radiotherapy, and photodynamic therapy, represents a recent …

[HTML][HTML] Immunogenic cell death in cancer: concept and therapeutic implications

L Galluzzi, O Kepp, E Hett, G Kroemer… - Journal of Translational …, 2023 - Springer
Mammalian cells responding to specific perturbations of homeostasis can undergo a
regulated variant of cell death that elicits adaptive immune responses. As immunogenic cell …

[HTML][HTML] Research progress in inducing immunogenic cell death of tumor cells

D Xie, Q Wang, G Wu - Frontiers in immunology, 2022 - frontiersin.org
Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …

[HTML][HTML] An overview on immunogenic cell death in cancer biology and therapy

MC Rodrigues, JAV Morais, R Ganassin, GRT Oliveira… - Pharmaceutics, 2022 - mdpi.com
Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to
promote an adaptive immune response against antigens of the dying cell in an …

The inducers of immunogenic cell death for tumor immunotherapy

X Li - Tumori Journal, 2018 - journals.sagepub.com
Immunotherapy is a promising treatment modality that acts by selectively harnessing the
host immune defenses against cancer. An effective immune response is often needed to …

Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy

I Adkins, J Fucikova, AD Garg, P Agostinis… - …, 2014 - Taylor & Francis
The concept of immunogenic cancer cell death (ICD), as originally observed during the
treatment with several chemotherapeutics or ionizing irradiation, has revolutionized the view …

[HTML][HTML] Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments

H Inoue, K Tani - Cell Death & Differentiation, 2014 - nature.com
Apoptotic cell death generally characterized by a morphologically homogenous entity has
been considered to be essentially non-immunogenic. However, apoptotic cancer cell death …

Cancer immunogenicity, danger signals, and DAMPs: what, when, and how?

AD Garg, AM Dudek, P Agostinis - Biofactors, 2013 - Wiley Online Library
Cancer immunosurvelliance usually leads to formation of cancer cells that have been
“immunoedited” to resist anti‐tumor immunity. One of the consequences of immunoediting …