The inflammation network in the pathogenesis of erectile dysfunction: attractive potential therapeutic targets

E Kaya-Sezginer, S Gur - Current Pharmaceutical Design, 2020 - ingentaconnect.com
Background: Erectile dysfunction (ED) is an evolving health problem in the aging male
population. Chronic low-grade inflammation is a critical component of ED pathogenesis and …

Inflammation, metabolic syndrome, erectile dysfunction, and coronary artery disease: common links

C Vlachopoulos, K Rokkas, N Ioakeimidis… - European urology, 2007 - Elsevier
OBJECTIVE: Erectile dysfunction (ED) may be the early clinical manifestation of a
generalized vascular disease and carries an independent risk for cardiovascular events …

Hypertension and erectile dysfunction: breaking down the challenges

AA de Oliveira, KP Nunes - American Journal of Hypertension, 2021 - academic.oup.com
A diagnostic of hypertension increases the risk of erectile dysfunction (ED); likewise, ED can
be an early sign of hypertension. In both cases, there is evidence that endothelial …

Imbalanced low-grade inflammation and endothelial activation in patients with type 2 diabetes mellitus and erectile dysfunction

MJ Araña Rosaínz, MO Ojeda, JR Acosta… - The journal of sexual …, 2011 - academic.oup.com
Introduction Erectile dysfunction (ED) is highly prevalent among type 2 diabetes mellitus
patients (T2DM). Although a link among systemic inflammation, endothelial dysfunction, and …

The efficacy of systemic inflammatory response and oxidative stress in erectile dysfunction through multi-inflammatory index: a prospective cross-sectional analysis

M Taskiran, K Dogan - The Journal of Sexual Medicine, 2023 - academic.oup.com
Background Systemic inflammation and oxidative stress increase the possibility of erectile
dysfunction (ED) through a coordinated response to vascular endothelial damage. Aim The …

Unfavourable endothelial and inflammatory state in erectile dysfunction patients with or without coronary artery disease

C Vlachopoulos, K Aznaouridis… - European heart …, 2006 - academic.oup.com
Aims Erectile dysfunction (ED) confers an independent cardiovascular risk. We investigated
the role of low-grade inflammation and endothelial dysfunction in ED patients with or without …

From inflammation to sexual dysfunctions: a journey through diabetes, obesity, and metabolic syndrome

MI Maiorino, G Bellastella, D Giugliano… - Journal of …, 2018 - Springer
Metabolic diseases are associated with chronic low-grade inflammation, which has been
indicated as a potential mediator of endothelial dysfunction and cardiovascular disease …

The triad: erectile dysfunction-endothelial dysfunction-cardiovascular disease

C Vlachopoulos, N Ioakeimidis… - Current …, 2008 - ingentaconnect.com
Endothelial dysfunction is an important process in the development of atherosclerotic
cardiovascular disease, while it is also a major pathophysiological mechanism underlying …

Pathophysiology of erectile dysfunction

H Matsui, NA Sopko, JL Hannan… - Current drug …, 2015 - ingentaconnect.com
Erectile dysfunction (ED) is a major health problem as the population ages. Basic science
research for the last two decades has expanded the knowledge on ED and identified several …

Endothelial dysfunction, erectile deficit and cardiovascular disease: an overview of the pathogenetic links

F De Leonardis, G Colalillo, E Finazzi Agrò, R Miano… - Biomedicines, 2022 - mdpi.com
Erectile dysfunction (ED) is a condition with multifactorial pathogenesis, quite common
among men, especially those above 60 years old. A vascular etiology is the most common …