Introduction Genetic disposition is a major etiologic factor in childhood cancer. More than
100 cancer predisposing syndromes (CPS) are known. Surveillance protocols seek to …

Cancer predisposition syndromes (CPS), or genetic syndromes leading to increased cancer
risk, are responsible for at least 10% of all childhood cancers. With advances in both tumor …

Expert recommendations for the management of tumor surveillance in children with a variety
of cancer predisposition syndromes (CPS) are available. We aimed (1) at identifying and …

Identification of patients with cancer predisposition syndromes (CPSs) can provide vital
information to guide care of an existing cancer, survey for future malignancy, and counsel …

In this issue of Pediatric Annals, we endeavored to provide a series of reviews to provide the
general practitioner with a broad overview of the concepts behind precision medicine as it …

Importance To improve diagnostics of cancer predisposition syndromes (CPSs) in children
with cancer, it is essential to evaluate the effect of CPS gene sequencing among all children …

It is estimated that at least 8% to 10% of children diagnosed with cancer have an inherited
cancer predisposition syndrome. Pediatricians may be called upon to (1) identify children …

Cancer predisposition syndromes (CPS) are underdiagnosed in the pediatric population,
though the diagnosis of a CPS has important implications for the child and their family. CPS …

Approximately 10% of children with newly diagnosed cancer have a cancer predisposition
syndrome (CPS). The optimal diagnostic approach to identify them among children …

Importance Pediatric oncology patients are increasingly recognized as having an underlying
cancer predisposition syndrome (CPS). Surveillance is often recommended to detect new …