[HTML][HTML] Immune modulation and possible pathological implications mediated by naturally produced immunoglobulin G idiotypes: from historical to recent experimental …

L Santander, NR Machado, BO Fagundes… - Clinical and …, 2024 - ncbi.nlm.nih.gov
Since the 1950s decade, it has been suggested that a naturally produced or induced
repertoire of immunoglobulin G (IgG) idiotypes may exert some immunoregulatory functions …

[PDF][PDF] Lucas Santander1, Nicolle Rakanidis Machado2, Beatriz Oliveira Fagundes2

JR Victor - ecevr.org
Since the 1950s decade, it has been suggested that a naturally produced or induced
repertoire of immunoglobulin G (IgG) idiotypes may exert some immunoregulatory functions …

Mechanism underlying polyvalent IgG-induced regulatory T cell activation and its clinical application: anti-idiotypic regulatory T cell theory for immune tolerance

JR Victor, DH Nahm - Frontiers in Immunology, 2023 - frontiersin.org
The regulatory T (Treg) cells constitute a functionally defined subpopulation of T cells that
modulate the immune system and maintain immune tolerance through suppression of the …

Local but not systemic administration of IFN-γ during the sensitization phase of protein antigen immunization suppress Th2 development in a murine model of atopic …

LF Wang, JT Wu, CC Sun - Cytokine, 2002 - Elsevier
Biphasic Th1/Th2 development plays a central role in the pathogenesis of atopic dermatitis.
In the sensitization phase after protein antigen exposure, an immune response polarized …

IgG subclasses determine pathways of anaphylaxis in mice

H Beutier, CM Gillis, B Iannascoli, O Godon… - Journal of Allergy and …, 2017 - Elsevier
Background Animal models have demonstrated that allergen-specific IgG confers sensitivity
to systemic anaphylaxis that relies on IgG Fc receptors (FcγRs). Mouse IgG 2a and IgG 2b …

Investigation of a syngeneic murine model for the study of IgE antibody regulation with isologous antiidiotypic antibodies

K Blaser, T Nakagawa, AL De Weck - International Archives of Allergy …, 1981 - karger.com
A murine experimental model to study in vivo effects of antiidiotypic antibodies (aid) on the
benzylpenicilloyl-(BPO) and phosphorylcholine-(PC) specific IgE and IgG responses has …

[HTML][HTML] Alternative Immunomodulatory and Disease-Modifying Treatment for Atopic Dermatitis: Autologous Total Immunoglobulin G

SM Kim, CO Park - Allergy, Asthma & Immunology Research, 2020 - ncbi.nlm.nih.gov
Trial” in volume 12 on page 949. inferred that the main immunomodulatory effect of AIGT
might be achieved through regulatory T-cell response which was suggested by the …

IgG subclasses in atopic eczema

RC Aalberse - Handbook of atopic eczema, 1991 - Springer
Atopic eczema (AE) is often accompanied by abnormalities in the humoral immune system.
Most striking in this respect is often a marked increase in IgE production. However …

Mechanism (s) of prolonged attenuation of allergic responses after modulation of idiotypic regulatory network

RM Gorczynski, T Maqbool, G Hoffmann - Allergy, Asthma & Clinical …, 2019 - Springer
Background We showed previously that allergic reactivity to ovalbumin (OVA) could be
regulated in mice following perturbation of immune networks using combinations of an …

Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies

W Hoepel, K Golebski, CM van Drunen… - Journal of Allergy and …, 2020 - jacionline.org
The antibody repertoire at mucosal sites consists mostly of IgA and IgG and is tailored to the
individual's microbiome. 1 Recently, a series of findings uncovered new functions of …