A new genomic blueprint of the human gut microbiota
The composition of the human gut microbiota is linked to health and disease, but knowledge
of individual microbial species is needed to decipher their biological roles. Despite …
of individual microbial species is needed to decipher their biological roles. Despite …
New insights from uncultivated genomes of the global human gut microbiome
The genome sequences of many species of the human gut microbiome remain unknown,
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …
Enterotypes of the human gut microbiome
M Arumugam, J Raes, E Pelletier, D Le Paslier… - nature, 2011 - nature.com
Our knowledge of species and functional composition of the human gut microbiome is
rapidly increasing, but it is still based on very few cohorts and little is known about variation …
rapidly increasing, but it is still based on very few cohorts and little is known about variation …
A human gut bacterial genome and culture collection for improved metagenomic analyses
Understanding gut microbiome functions requires cultivated bacteria for experimental
validation and reference bacterial genome sequences to interpret metagenome datasets …
validation and reference bacterial genome sequences to interpret metagenome datasets …
A high-quality genome compendium of the human gut microbiome of Inner Mongolians
Metagenome-based resources have revealed the diversity and function of the human gut
microbiome, but further understanding is limited by insufficient genome quality and a lack of …
microbiome, but further understanding is limited by insufficient genome quality and a lack of …
Culturing of 'unculturable'human microbiota reveals novel taxa and extensive sporulation
Our intestinal microbiota harbours a diverse bacterial community required for our health,
sustenance and wellbeing,. Intestinal colonization begins at birth and climaxes with the …
sustenance and wellbeing,. Intestinal colonization begins at birth and climaxes with the …
A library of human gut bacterial isolates paired with longitudinal multiomics data enables mechanistic microbiome research
Our understanding of how the gut microbiome interacts with its human host has been
restrained by limited access to longitudinal datasets to examine stability and dynamics, and …
restrained by limited access to longitudinal datasets to examine stability and dynamics, and …
1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses
Reference genomes are essential for metagenomic analyses and functional characterization
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …
The genomic landscape of reference genomes of cultivated human gut bacteria
X Lin, T Hu, J Chen, H Liang, J Zhou, Z Wu… - Nature …, 2023 - nature.com
Culture-independent metagenomic studies have revolutionized our understanding of the gut
microbiota. However, the lack of full genomes from cultured species is still a limitation for in …
microbiota. However, the lack of full genomes from cultured species is still a limitation for in …
A human gut microbial gene catalogue established by metagenomic sequencing
To understand the impact of gut microbes on human health and well-being it is crucial to
assess their genetic potential. Here we describe the Illumina-based metagenomic …
assess their genetic potential. Here we describe the Illumina-based metagenomic …