Lipids and secretory vesicle exocytosis

IO Akefe, SL Osborne, B Matthews, TP Wallis… - Molecular Mechanisms …, 2023 - Springer
In recent years, the number of studies implicating lipids in the regulation of synaptic vesicle
exocytosis has risen considerably. It has become increasingly clear that lipids such as …

Lipid dynamics in exocytosis

S Chasserot-Golaz, JR Coorssen, FA Meunier… - Cellular and molecular …, 2010 - Springer
Regulated exocytosis of neurotransmitter-and hormone-containing vesicles underpins
neuronal and hormonal communication and relies on a well-orchestrated series of …

Lipid regulation of the synaptic vesicle cycle

J Rohrbough, K Broadie - Nature Reviews Neuroscience, 2005 - nature.com
Membrane vesicle cycling is orchestrated through the combined actions of proteins and
lipids. At neuronal synapses, this orchestration must meet the stringent demands of speed …

Phosphoinositide regulation of neuroexocytosis: adding to the complexity

SL Osborne, PJ Wen, FA Meunier - Journal of neurochemistry, 2006 - Wiley Online Library
Exocytosis of neurotransmitter containing vesicles supports neuronal communication. The
importance of molecular interactions involving specific lipids has become progressively …

Cholesterol and synaptic vesicle exocytosis

P Rosa, A Fratangeli - Communicative & Integrative Biology, 2010 - Taylor & Francis
Lipids may affect synaptic function in at least two ways: by acting as ligands for effector
proteins (eg phosphatidylinositol (4, 5) bisphosphate, diacylglycerol-mediated signalling) or …

[HTML][HTML] An overview of the synaptic vesicle lipid composition

B Binotti, R Jahn, Á Pérez-Lara - Archives of Biochemistry and Biophysics, 2021 - Elsevier
Chemical neurotransmission is the major mechanism of neuronal communication.
Neurotransmitters are released from secretory organelles, the synaptic vesicles (SVs) via …

Greasing the synaptic vesicle cycle by membrane lipids

D Puchkov, V Haucke - Trends in cell biology, 2013 - cell.com
Neurotransmission is based on the exocytic release of neurotransmitters from synaptic
vesicles (SVs) at nerve terminals and the subsequent retrieval of SV membranes. Evidence …

Lipid function at synapses

B Davletov, C Montecucco - Current opinion in neurobiology, 2010 - Elsevier
Chemical neurotransmission between neurons is a major point for modulation of neuronal
activity. The neuronal synapse is the site of continuous cycles of rapid vesicle fusion …

Diacylglycerol, phosphatidic acid, and their metabolic enzymes in synaptic vesicle recycling

B Tu-Sekine, H Goldschmidt, DM Raben - Advances in biological …, 2015 - Elsevier
The synaptic vesicle (SV) cycle includes exocytosis of vesicles loaded with a
neurotransmitter such as glutamate, coordinated recovery of SVs by endocytosis, refilling of …

Phospholipase Modulation of Synaptic Membrane Landscape: Driving Force Behind Memory Formation?

TP Wallis, FA Meunier - Cold Spring Harbor Perspectives …, 2024 - cshperspectives.cshlp.org
The synapse is the communication unit of the brain, linking billions of neurons through
trillions of synaptic connections. The lipid landscape of the synaptic membrane underpins …