Combined Metabolome and Lipidome Analyses for In-Depth Characterization of Lipid Accumulation in the DHA Producing Aurantiochytrium sp. T66

Z Bartosova, H Ertesvåg, EL Nyfløt, K Kämpe, IM Aasen… - Metabolites, 2021 - mdpi.com
Thraustochytrids are marine heterotrophic microorganisms known for their potential to
accumulate docosahexaenoic acid (DHA)-enriched lipids. There have been many attempts …

Revealing holistic metabolic responses associated with lipid and docosahexaenoic acid (DHA) production in Aurantiochytrium sp. SW1

P Prabhakaran, N Raethong, R Thananusak… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Aurantiochytrium sp. SW1, a marine thraustochytrid, has been regarded as a potential
candidate as a docosahexaenoic acid (DHA) producer. Even though the genomics of …

Uncovering global lipid accumulation routes towards docosahexaenoic acid (DHA) production in Aurantiochytrium sp. SW1 using integrative proteomic analysis

P Prabhakaran, MYM Nazir, R Thananusak… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Aurantiochytrium sp., a marine thraustochytrid possesses a remarkable ability to produce
lipid rich in polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) …

High‐quality genome‐scale metabolic model of Aurantiochytrium sp. T66

V Simensen, A Voigt, E Almaas - Biotechnology and …, 2021 - Wiley Online Library
Abstract The long‐chain, ω‐3 polyunsaturated fatty acids (PUFAs)(eg, eicosapentaenoic
acid [EPA] and docosahexaenoic acid [DHA]), are essential for humans and animals …

Lipid and DHA-production in Aurantiochytrium sp. – Responses to nitrogen starvation and oxygen limitation revealed by analyses of production kinetics and global …

TMB Heggeset, H Ertesvåg, B Liu, TE Ellingsen… - Scientific Reports, 2019 - nature.com
Thraustochytrids of the genera Schizochytrium and Aurantiochytrium accumulate oils rich in
the essential, marine n3 fatty acid docosahexaenoic acid (DHA). DHA production in …

Delineating metabolomic changes in native isolate Aurantiochytrium for production of docosahexaenoic acid in presence of varying carbon substrates

I Mariam, MS Kareya, AA Nesamma, PP Jutur - Algal Research, 2021 - Elsevier
Oils rich in polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (DHA) have
industrial significance due to their benefits in human nutrition and health. In this context, our …

A thraustochytrid-specific lipase/phospholipase with unique positional specificity contributes to microbial competition and fatty acid acquisition from the environment

Y Ishibashi, K Aoki, N Okino, M Hayashi, M Ito - Scientific reports, 2019 - nature.com
Thraustochytrids are heterotrophic marine protists that are considered as important
decomposers in the marine ecosystem; however, how they digest and uptake lipid nutrients …

An Oil Hyper-Accumulator Mutant Highlights Peroxisomal ATP Import as a Regulatory Step for Fatty Acid Metabolism in Aurantiochytrium limacinum

E Deragon, M Schuler, R Aiese Cigliano, Y Dellero… - Cells, 2021 - mdpi.com
Thraustochytrids are marine protists that naturally accumulate triacylglycerol with long
chains of polyunsaturated fatty acids, such as ω3-docosahexaenoic acid (DHA). They …

Low dissolved oxygen supply functions as a global regulator of the growth and metabolism of Aurantiochytrium sp. PKU#Mn16 in the early stages of …

L Liu, X Zhu, H Ye, Y Wen, B Sen, G Wang - Microbial Cell Factories, 2023 - Springer
Background Thraustochytrids accumulate lipids with a high content of docosahexaenoic
acid (DHA). Although their growth and DHA content are significantly affected by the …

Nitrogen Starvation Enhances the Production of Saturated and Unsaturated Fatty Acids in Aurantiochytrium sp. PKU#SW8 by Regulating Key Biosynthetic Genes

X Chen, Y He, L Liu, X Zhu, B Sen, G Wang - Marine Drugs, 2022 - mdpi.com
Nitrogen deprivation is known to improve lipid accumulation in microalgae and
thraustochytrids. However, the patterns of fatty acid production and the molecular …