Heart failure is a devastating condition, the progression of which culminates in a mismatch of
oxygen supply and demand, with limited options for treatment. Heart failure has several …

Therapeutic angiogenesis for heart failure | Nature Medicine Skip to main content Thank you for
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Members of the vascular endothelial growth factor (VEGF) family are among the most
powerful modulators of vascular biology. They regulate vasculogenesis, angiogenesis, and …

In diabetes, compromised glucose utilization leads the heart to use FA almost exclusively for
ATP generation. Chronically, this adaptation unfortunately leads to the conversion of FA to …

Despite the enormous progress made in terms of prevention and early intervention, a
pressing need remains to develop innovative therapeutic strategies for ischemic …

Despite major advances in medical, catheter-based or surgical treatment, cardiovascular
diseases such as peripheral artery disease and coronary artery disease still cause …

Mounting evidence indicates that the function of members of the vascular endothelial growth
factor (VEGF) family extends beyond blood vessel formation. Here, we show that the …

There is widespread interest in the use of the angiogenic cytokine, vascular endothelial
growth factor (VEGF), for the treatment of cardiovascular disease. The main paradigm for …

Background: Vascular endothelial growth factor (VEGF)-B activates cytoprotective/
antiapoptotic and minimally angiogenic mechanisms via VEGF receptors. Therefore, VEGF …

The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …