Abstract Knowledge of the stability of drugs in biological samples is important for the
interpretation of toxicological findings. This paper reviews data on the stability of drugs in …

Knowledge of the stability of drugs in biological specimens is a critical consideration for the
interpretation of analytical results. Identification of proper storage conditions has been a …

Evaluation of the stability of drugs and drug metabolites in a biological matrix is a critical
element to bioanalytical method validation. It is critical to understand the most common …

Stability is one of the basic parameters, along with accuracy, precision, selectivity, and
sensitivity, for bioanalytic method validation in nonhuman and clinical pharmacology …

Stability is an important consideration in the use of specimens for accurate determination of
analyte concentrations. To determine the long-term stability for analytes routinely analyzed …

Isolated studies of the stability of individual drugs of abuse have been reported. However,
few have evaluated stability in frozen urine samples stored for 12 months. We have …

The stability of 30 common antipsychotics (APs) in spiked whole blood was investigated
over ten weeks in a preliminary experiment (designated “P experiment”). Pools of blank …

The present study was designed to determine the stability of common illicit drugs in stored
blood at various time intervals for a period of up to 5 years. The drugs of interest were …

This write-up provides a review on the development of validated stability-indicating assay
methods (SIAMs) for drug substances and products. The shortcomings of reported methods …

Study has been undertaken to determine the stability of four benzodiazepines: clonazepam,
midazolam, flunitrazepam and oxazepam in whole blood samples. Spiked blood was stored …