What can we learn about schizophrenia from studying the human model, drug‐induced psychosis?

RM Murray, A Paparelli, PD Morrison… - American Journal of …, 2013 - Wiley Online Library
When drug‐induced psychoses were first identified in the mid‐20th century, schizophrenia
was considered a discrete disease with a likely genetic cause. Consequently, drug‐induced …

Genetics of schizophrenia: from animal models to clinical studies

R Joober, P Boksa, C Benkelfat, G Rouleau - Journal of Psychiatry and …, 2002 - jpn.ca
Genetic epidemiological studies strongly suggest that additive and interactive genes, each
with small effects, mediate the genetic vulnerability for schizophrenia. With the human …

[PDF][PDF] Genetic predisposition to schizophrenia: what did we learn and what does the future hold

A Vereczkei, K Mirnics - Neuropsychopharmacol Hung, 2011 - researchgate.net
Schizophrenia is a complex, devastating brain disorder with clear genetic and
environmental contributions to the emergence of the disease. In the last several decades of …

[PDF][PDF] Endophenotypes in studies of the genetics of schizophrenia

DL Braff, R Freedman - … : The Fifth Generation of Progress: An Official …, 2002 - Citeseer
The power and appeal of the molecular biology mantra,''DNA to RNA to protein,''to explicate
cell biology comes from its universal appearance and application in all species, from …

New findings in pharmacogenetics of schizophrenia

CC Zai, AK Tiwari, GC Zai, MS Maes… - Current opinion in …, 2018 - journals.lww.com
The findings to date are promising and provide us a better understanding of the
development of side effects and response to antipsychotics. However, more comprehensive …

Molecular genetics of schizophrenia: a critical review

N Berry, V Jobanputra, H Pal - Journal of Psychiatry and Neuroscience, 2003 - jpn.ca
We present an overview of current progress and future directions in the molecular genetics
of schizophrenia. We review linkage studies, involving the genome-wide scan of …

Drug-induced psychosis: how to avoid star gazing in schizophrenia research by looking at more obvious sources of light

A Paparelli, M Di Forti, PD Morrison… - Frontiers in behavioral …, 2011 - frontiersin.org
The prevalent view today is that schizophrenia is a syndrome rather than a specific disease.
Liability to schizophrenia is highly heritable. It appears that multiple genetic and …

Schizotypy—do not worry, it is not all worrisome

C Mohr, G Claridge - Schizophrenia bulletin, 2015 - academic.oup.com
A long-standing tradition in personality research in psychology, and nowadays increasingly
in psychiatry, is that psychotic and psychotic-like thoughts are considered common …

Schizophrenia: a review of genetic studies

MT Tsuang, WS Stone, SV Faraone - Harvard Review of Psychiatry, 1999 - Taylor & Francis
Despite the complexities of schizophrenia, notable progress has been achieved in its
diagnosis and treatment over the last 25 years. In this article we review the genetic research …

New genetic findings in schizophrenia: is there still room for the dopamine hypothesis of schizophrenia?

V Nieratschker, MM Nöthen… - Frontiers in behavioral …, 2010 - frontiersin.org
Schizophrenia is a highly heritable disorder, but the identification of specific genes has
proven to be a difficult endeavour. Genes involved in the dopaminergic system are …