Epitope Mapping of an Anti-Mouse CXCR6 Monoclonal Antibody (Cx6Mab-1) Using the 2 × Alanine Scanning Method

Y Isoda, T Tanaka, H Suzuki, T Asano… - Monoclonal …, 2022 - liebertpub.com
The CXC chemokine receptor 6 (CXCR6) is a member of the G protein-coupled receptor
family that is highly expressed in helper T type 1 cells, cytotoxic T lymphocytes (CTLs), and …

Cx6Mab-1: A Novel Anti-Mouse CXCR6 Monoclonal Antibody Established by N-Terminal Peptide Immunization

K Kitamura, H Suzuki, MK Kaneko… - Monoclonal Antibodies in …, 2022 - liebertpub.com
The CXC chemokine receptor 6 (CXCR6) is a member of the G protein-coupled receptor
family that is highly expressed in helper T type 1 cells, natural killer cells, cytotoxic T …

Epitope Mapping Using the Cell-Based 2 × Alanine Substitution Method About the Anti-mouse CXCR6 Monoclonal Antibody, Cx6Mab-1

Y Isoda, T Tanaka, H Suzuki, T Asano… - Monoclonal …, 2023 - liebertpub.com
An anti-mouse CXC chemokine receptor 6 (mCXCR6) monoclonal antibody (mAb), Cx6Mab-
1, was developed recently. Cx6Mab-1 is applicable for flow cytometry, Western blotting, and …

Cx4Mab-1: A Novel Anti-Mouse CXCR4 Monoclonal Antibody for Flow Cytometry

T Ouchida, H Suzuki, T Tanaka… - Monoclonal antibodies …, 2024 - liebertpub.com
The CXC chemokine receptor 4 (CXCR4, CD184) is a member of the G protein-coupled
receptor family that is expressed in most leukocytes. Overexpression of CXCR4 is …

Cx1Mab-1: A Novel Anti-mouse CXCR1 Monoclonal Antibody for Flow Cytometry

G Li, T Tanaka, T Ouchida, MK Kaneko… - Monoclonal …, 2024 - liebertpub.com
The CXC motif chemokine receptor-1 (CXCR1) is a rhodopsin-like G-protein-coupled
receptor, expressed on the cell surface of immune cells and tumors. CXCR1 interacts with …

Immunotherapy of B‐cell non‐Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model

H Panjideh, G Müller, M Koch, F Wilde… - … journal of cancer, 2014 - Wiley Online Library
Bispecific antibodies are promising agents for immunotherapy. Here, we describe a
quadroma‐based trifunctional bispecific antibody binding the chemokine receptor CXCR5 …

[HTML][HTML] Reassessment of CXCR4 chemokine receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-2

T Fischer, F Nagel, S Jacobs, R Stumm, S Schulz - PLoS One, 2008 - journals.plos.org
Background The CXCR4 chemokine receptor regulates migration and homing of cancer
cells to specific metastatic sites. Determination of the CXCR4 receptor status will provide …

Epitope Mapping of an Anti-Mouse CCR8 Monoclonal Antibody C8Mab-2 Using Flow Cytometry

H Kobayashi, H Suzuki, T Tanaka… - Monoclonal Antibodies …, 2024 - liebertpub.com
The CC motif chemokine receptor 8 (CCR8) is highly and selectively expressed in regulatory
T (Treg) cells and is associated with tumor progression. The massive accumulation of Treg …

The CXCR3 targeting chemokine CXCL11 has potent antitumor activity in vivo involving attraction of CD8+ T lymphocytes but not inhibition of angiogenesis

PJ Hensbergen, PGJTB Wijnands… - Journal of …, 2005 - journals.lww.com
The IFN-γ-inducible and CXCR3-targeting human CXC chemokines CXCL9 (Mig) and
CXCL10 (IP10) have potent antitumor activity through attraction of cytotoxic T lymphocytes …

[HTML][HTML] Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C9Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method

H Kobayashi, T Asano, T Tanaka, H Suzuki… - Antibodies, 2023 - mdpi.com
CC chemokine receptor 9 (CCR9) is a receptor for CC-chemokine ligand 25 (CCL25). CCR9
is crucial in the chemotaxis of immune cells and inflammatory responses. Moreover, CCR9 …