New strategies in mechanical ventilation for acute lung injury

H Burchardi - European Respiratory Journal, 1996 - Eur Respiratory Soc
In the fluid-filled lungs of early adult respiratory distress syndrome (ARDS) the dependent
parts are compressed and atelectatic; whereas, the nondependent areas remain aerated …

Positive end-expiratory pressure in acute respiratory distress syndrome: should the'open lung strategy'be replaced by a'protective lung strategy'?

JJ Rouby, F Ferrari, B Bouhemad, Q Lu - Critical Care, 2007 - Springer
In patients with acute respiratory distress syndrome, positive end-expiratory pressure is
associated with alveolar recruitment and lung hyperinflation despite the administration of a …

Acute respiratory distress syndrome, the critical care paradigm: what we learned and what we forgot

L Gattinoni, E Carlesso, F Valenza… - Current opinion in …, 2004 - journals.lww.com
In the last several years, we definitely learned that the acute respiratory distress syndrome
lung is small, nonhomogeneous, and that mechanical ventilation in this baby lung may …

Applications of airway pressure release ventilation

J Porhomayon, AA El-Solh, ND Nader - Lung, 2010 - Springer
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How ARDS should be treated

L Gattinoni, M Quintel - Critical Care, 2016 - Springer
The Berlin definition criteria applied at positive end-expiratory pressure (PEEP) 5 cm H 2 O
reasonably predict lung edema and recruitabilty. To maintain viable gas exchange, the …

Airway pressure release ventilation during acute lung injury: a prospective multicenter trial

J RÄSÄNEN, ROYD CANE, JB DOWNS… - Critical care …, 1991 - journals.lww.com
Objective: To evaluate the feasibility of airway pressure release ventilation (APRV) in
providing ventilatory support to patients with acute lung injury of diverse etiology and mild-to …

How to ventilate patients with acute lung injury and acute respiratory distress syndrome

L Gattinoni, P Caironi, E Carlesso - Current opinion in critical care, 2005 - journals.lww.com
Gentle lung ventilation must be standard practice. Because stress and strain are the triggers
of ventilator-induced lung injury, their clinical equivalents should be measured …

Recent advances in mechanical ventilation

CS Calfee, MA Matthay - The American journal of medicine, 2005 - Elsevier
Important advances have been made over the past decade towards understanding the
optimal approach to ventilating patients with acute respiratory failure. Evidence now …

Acute lung injury: pathophysiology, assessment and current therapy

J Hammer - Paediatric respiratory reviews, 2001 - Elsevier
Acute respiratory distress syndrome (ARDS) is a clinically defined entity describing the
severity of diffuse alveolar injury caused by direct or indirect injury to the lung …

New options for the ventilatory management of acute lung injury.

JJ Marini - New horizons (Baltimore, Md.), 1993 - europepmc.org
The traditional practice of using high inflation pressures to maintain normal tidal volumes
and arterial blood gases has been encouraged by the perception of uniformly distributed …