Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies
GM Morriss‐Kay, AOM Wilkie - Journal of anatomy, 2005 - Wiley Online Library
The mammalian skull vault is constructed principally from five bones: the paired frontals and
parietals, and the unpaired interparietal. These bones abut at sutures, where most growth of …
parietals, and the unpaired interparietal. These bones abut at sutures, where most growth of …
Craniosynostosis: genes and mechanisms
AOM Wilkie - Human molecular genetics, 1997 - academic.oup.com
Enlargement of the skull vault occurs by appositional growth at the fibrous joints between the
bones, termed cranial sutures. Relatively little is known about the developmental biology of …
bones, termed cranial sutures. Relatively little is known about the developmental biology of …
The development of the calvarial bones and sutures and the pathophysiology of craniosynostosis
The skull vault is a complex, exquisitely patterned structure that plays a variety of key roles in
vertebrate life, ranging from the acquisition of food to the support of the sense organs for …
vertebrate life, ranging from the acquisition of food to the support of the sense organs for …
Cranial vault growth in craniosynostosis
JB Delashaw, JA Persing, WC Broaddus… - Journal of neurosurgery, 1989 - thejns.org
✓ Skull growth after single suture closure was described in 1851 by Virchow, who noted that
growth in the plane perpendicular to a fused suture was restricted. However, this …
growth in the plane perpendicular to a fused suture was restricted. However, this …
Cranial sutures as intramembranous bone growth sites
LA Opperman - … dynamics: an official publication of the …, 2000 - Wiley Online Library
Intramembranous bone growth is achieved through bone formation within a periosteum or
by bone formation at sutures. Sutures are formed during embryonic development at the sites …
by bone formation at sutures. Sutures are formed during embryonic development at the sites …
Understanding craniosynostosis as a growth disorder
K Flaherty, N Singh… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
Craniosynostosis is a condition of complex etiology that always involves the premature
fusion of one or multiple cranial sutures and includes various anomalies of the soft and hard …
fusion of one or multiple cranial sutures and includes various anomalies of the soft and hard …
Cranial deformation in craniosynostosis. A new explanation.
JB Delashaw, JA Persing, JA Jane - Neurosurgery Clinics of North …, 1991 - europepmc.org
Skull growth after premature fusion of a single suture was described by Virchow in 1851. He
observed that growth was restricted in a plane perpendicular to a fused suture. However, he …
observed that growth was restricted in a plane perpendicular to a fused suture. However, he …
[HTML][HTML] Development and growth of the normal cranial vault: an embryologic review
SW Jin, KB Sim, SD Kim - Journal of Korean Neurosurgical …, 2016 - synapse.koreamed.org
Understanding the development of a skull deformity requires an understanding of the normal
morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of …
morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of …
FGF-, BMP-and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development
HJ Kim, DPC Rice, PJ Kettunen, I Thesleff - Development, 1998 - journals.biologists.com
The development of calvarial bones is tightly co-ordinated with the growth of the brain and
needs harmonious interactions between different tissues within the calvarial sutures …
needs harmonious interactions between different tissues within the calvarial sutures …
9 Cranial Suture Biology
KA Lenton, RP Nacamuli, DC Wan… - Current topics in …, 2005 - books.google.com
The term craniosynostosis was first used in 1830 by Otto to describe the premature fusion of
cranial sutures (Otto, 1830). Since this first identification of craniosynostosis as a distinct …
cranial sutures (Otto, 1830). Since this first identification of craniosynostosis as a distinct …