Late-stage diversification of structurally complex amino acids and peptides provides
tremendous potential for drug discovery and molecular imaging. Specifically, labeling …

The late-stage fluorescent labeling of structurally complex peptides bears immense potential
for molecular imaging. Herein, we report on a manganese (I)-catalyzed peptide C–H …

Bioorthogonal late-stage diversification of amino acids and peptides bears enormous
potential for drug discovery and molecular imaging. Despite major accomplishments, these …

Bioorthogonal late-stage diversification of structurally complex peptides bears enormous
potential for drug discovery and molecular imaging. Despite major accomplishments, these …

The site‐selective chemical diversification of biomolecules constitutes an unmet challenge
of capital importance within medicinal chemistry and chemical biology. The functionalization …

Bioorthogonal C− H allylation with ample scope was accomplished through a versatile
manganese (I)‐catalyzed C− H activation for the late‐stage diversification of structurally …

Late-stage peptide modification showcases a huge potential for the construction of peptide
libraries, and the investigation of structure–activity relationships. Herein we report a dimethyl …

The development of useful synthetic tools to label amino acids within a peptide framework
for the ultimate modification of proteins in a late-stage fashion is a challenging task of utmost …

Postsynthetic diversification of peptides through selective modification of endogenous amino
acid side chains has enabled significant advances in peptide drug discovery while …

The field of peptide derivatization by metal‐catalyzed C− H activation has been mostly
directed to modify the side chains, but poor attention has been given to the peptide …