GABAA receptors: subtypes provide diversity of function and pharmacology
RW Olsen, W Sieghart - Neuropharmacology, 2009 - Elsevier
This mini-review attempts to update experimental evidence on the existence of GABAA
receptor pharmacological subtypes and to produce a list of those native receptors that exist …
receptor pharmacological subtypes and to produce a list of those native receptors that exist …
GABAA-receptor subtypes: a new pharmacology
H Möhler, F Crestani, U Rudolph - Current opinion in pharmacology, 2001 - Elsevier
The GABAA receptor is a pluripotent drug target mediating anxiolytic, sedative,
anticonvulsant, muscle relaxant and amnesic activity. These drug actions have now been …
anticonvulsant, muscle relaxant and amnesic activity. These drug actions have now been …
International Union of Pharmacology. LXX. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit composition, pharmacology, and function …
RW Olsen, W Sieghart - Pharmacological reviews, 2008 - ASPET
In this review we attempt to summarize experimental evidence on the existence of defined
native GABAA receptor subtypes and to produce a list of receptors that actually seem to exist …
native GABAA receptor subtypes and to produce a list of receptors that actually seem to exist …
Structure, pharmacology, and function of GABAA receptor subtypes
W Sieghart - Advances in pharmacology, 2006 - Elsevier
Publisher Summary This chapter describes the structure, pharmacology, and function of γ‐
aminobutyric acid type A (GABA A) receptor subtypes. GABA A receptors are the most …
aminobutyric acid type A (GABA A) receptor subtypes. GABA A receptors are the most …
GABAA receptor subtypes: from pharmacology to molecular biology
DR Burt, GL Kamatchi - The FASEB journal, 1991 - Wiley Online Library
GABAA receptors are GABA (γ‐amino‐butyric acid)‐gated chloride channels, which are
major mediators of neuronal inhibition in the brain and are modulated by benzodiazepines …
major mediators of neuronal inhibition in the brain and are modulated by benzodiazepines …
GABAA receptor channels: from subunits to functional entities
W Wisden, PH Seeburg - Current opinion in neurobiology, 1992 - Elsevier
GABA A receptor channels mediate postsynaptic inhibition. The functional diversity of these
receptors rests on differences in subunit composition and on a large repertoire of subunits …
receptors rests on differences in subunit composition and on a large repertoire of subunits …
The diversity of GABAA receptors: Pharmacological and electrophysiological properties of GABAA channel subtypes
W Hevers, H Lüddens - Molecular neurobiology, 1998 - Springer
The amino acid γ-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotrans-
mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABA AR) …
mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABA AR) …
Subunit composition, distribution and function of GABA-A receptor subtypes
W Sieghart, G Sperk - Current topics in medicinal chemistry, 2002 - ingentaconnect.com
GABA-A receptors are the major inhibitory neurotransmitter receptors in the brain and are
the site of action of many clinically important drugs. These receptors are composed of five …
the site of action of many clinically important drugs. These receptors are composed of five …
[图书][B] The GABA receptors
SJ Enna - 2007 - Springer
Abstract γ-Aminobutyric acid (GABA), an amino acid neurotransmitter, is widely distributed
throughout the neuraxis. Two pharmacologically and molecularly distinct GABA receptors …
throughout the neuraxis. Two pharmacologically and molecularly distinct GABA receptors …
International Union of Basic and Clinical Pharmacology. CVI: GABAA receptor subtype-and function-selective ligands: key issues in translation to humans
W Sieghart, MM Savić - Pharmacological reviews, 2018 - ASPET
GABAA receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …