The family of nuclear factor-kappaB (NF-κB) transcription factors is intimately involved in the
regulation of expression of numerous genes in the setting of the inflammatory response …

Nuclear factor-kappaB (NF-κB) proteins constitute a family of transcription factors that are
stimulated by pro-inflammatory cytokines, chemokines, stress-related factors and …

The transcription factor NF-κB has been well recognized as a pivotal regulator of
inflammation in rheumatoid arthritis (RA), but recent developments revealed a broad …

In the synovial cells of patients with RA, activation of the nuclear factor-κB (NF-κB) pathway
results in the transactivation of a multitude of responsive genes that contribute to the …

The nuclear factor-κB (NF-κB) family of transcription factors is essential for the expression of
pro-inflammatory cytokines, but can also induce regulatory pathways. NF-κB can be …

Nuclear factor-κB (NF-κB) is an inducible transcription factor controlled by two principal
signaling cascades, each activated by a set of signal ligands: the classical/canonical NF-κB …

The transcription factor NF-κB is a pivotal regulator of inflammatory responses. While the
activation of NF-κB in the arthritic joint has been associated with rheumatoid arthritis (RA), its …

The nuclear factor-κB (NF-κB) is a transcription factor that regulates the expression of genes
that control cell proliferation and apoptosis, as well as genes that respond to inflammation …

The transcription factor NF-κB plays crucial roles in the regulation of inflammation and
mmune responses, and inappropriate NF-κB activity has been linked with many autoimmune …

Recent advances in our understanding of the role of cytokine networks in inflammatory
processes have led to the development of novel biological agents for the treatment of …