The TGFβ signaling pathway has pleiotropic functions regulating cell growth, differentiation,
apoptosis, motility and invasion, extracellular matrix production, angiogenesis, and immune …

The transforming growth factor‐β (TGF‐β) is a family of structurally related proteins that
comprises of TGF‐β, activins/inhibins, and bone morphogenic proteins (BMPs). Members of …

Transforming growth factor-β (TGFβ) family members are structurally and functionally related
cytokines that have diverse effects on the regulation of cell fate during embryonic …

Introduction: The transforming growth factor-β (TGF-β) signaling pathway has a pivotal role
in tumor suppression and yet, paradoxically, in tumor promotion. Functional context …

TGF-β pathway is being extensively evaluated as a potential therapeutic target. The
transforming growth factor-β (TGF-β) signaling pathway has the dual role in both tumor …

TGFβ signalling has key roles in cancer progression: most carcinoma cells have inactivated
their epithelial antiproliferative response and benefit from increased TGFβ expression and …

TGF-β is a ubiquitous cytokine that plays an active role in many cellular processes. Nearly
every cell type has the ability to secrete TGF-β, as well as the ability to respond to TGF-β via …

During the past decades, drugs targeting transforming growth factor-β (TGFβ) signaling have
received tremendous attention for late-stage cancer treatment since TGFβ signaling has …

Signals from the transforming growth factor-β (TGF-β) superfamily mediate a broad spectrum
of cellular processes and are deregulated in many diseases, including cancer. TGF-β …

Transforming growth factor β (TGF-β) signaling pathway has pleiotropic effects on cell
proliferation, differentiation, adhesion, senescence, and apoptosis. TGF-β can be widely …