Designing hydrogels for controlled drug delivery

J Li, DJ Mooney - Nature Reviews Materials, 2016 - nature.com
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Nanocarrier‐hydrogel composite delivery systems for precision drug release

LE Kass, J Nguyen - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Hydrogels are a class of biomaterials widely implemented in medical applications due to
their biocompatibility and biodegradability. Despite the many successes of hydrogel‐based …

[HTML][HTML] Role of polymer concentration and crosslinking density on release rates of small molecule drugs

F Briggs, D Browne, P Asuri - International Journal of Molecular Sciences, 2022 - mdpi.com
Over the past few years, researchers have demonstrated the use of hydrogels to design drug
delivery platforms that offer a variety of benefits, including but not limited to longer circulation …

Hydrogels with smart systems for delivery of hydrophobic drugs

D Gu, AJ O'Connor, G GH Qiao… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Smart hydrogel systems present opportunities to not only provide hydrophobic
molecule encapsulation capability but to also respond to specific delivery routes. Areas …

Hydrogels in controlled release formulations: network design and mathematical modeling

CC Lin, AT Metters - Advanced drug delivery reviews, 2006 - Elsevier
Over the past few decades, advances in hydrogel technologies have spurred development
in many biomedical applications including controlled drug delivery. Many novel hydrogel …

Hydrogel-based controlled drug delivery for cancer treatment: a review

Z Sun, C Song, C Wang, Y Hu, J Wu - Molecular pharmaceutics, 2019 - ACS Publications
As an emerging drug carrier, hydrogels have been widely used for tumor drug delivery. A
hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and …

[HTML][HTML] Modular hydrogels for drug delivery

S Sim, A Figueiras, F Veiga - 2012 - scirp.org
The development of novel drug delivery systems is an essential step toward controlled site-
specific administration of therapeutics within the body. It is desirable for delivery vehicles to …

[HTML][HTML] Polymer-based hydrogels applied in drug delivery: An overview

NH Thang, TB Chien, DX Cuong - Gels, 2023 - mdpi.com
Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied
for drug delivery applications because of their ability to hold large amounts of water and …

Hydrogels in a historical perspective: From simple networks to smart materials

SJ Buwalda, KWM Boere, PJ Dijkstra, J Feijen… - Journal of controlled …, 2014 - Elsevier
Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

[HTML][HTML] Hydrogel-based drug delivery systems for poorly water-soluble drugs

M McKenzie, D Betts, A Suh, K Bui, LD Kim, H Cho - Molecules, 2015 - mdpi.com
Hydrogels are three-dimensional materials that can withstand a great amount of water
incorporation while maintaining integrity. This allows hydrogels to be very unique …