Frontal cortex is thought to underlie many advanced cognitive capacities, from self-control to
long term planning. Reflecting these diverse demands, frontal neural activity is notoriously …

The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

Motivation exerts control over behavior by eliciting Pavlovian responses, which can either
match or conflict with instrumental action. We can overcome maladaptive motivational …

Cognitive flexibility is fundamental to adaptive intelligent behavior. Prefrontal cortex has long
been associated with flexible cognitive function, but the neurophysiological principles that …

Prefrontal cortex and cognitive control: motivating functional hierarchies | Nature Neuroscience
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The prefrontal cortex (PFC) provides the structural basis for complex rule-guided goal-
directed behavior. However, the functional mechanisms that underlie cognitive control and …

The prefrontal cortex (PFC) provides the structural basis for numerous higher cognitive
functions. However, it is still largely unknown which mechanisms provide the functional …

Prefrontal cortex is thought to have a fundamental role in flexible, context-dependent
behaviour, but the exact nature of the computations underlying this role remains largely …

Adaptive behavior requires context-sensitive configuration of task-sets that specify time-
varying stimulus–response mappings. Intriguingly, response time costs associated with …

▪ Abstract The prefrontal cortex has long been suspected to play an important role in
cognitive control, in the ability to orchestrate thought and action in accordance with internal …