Background The options for secondary prevention of cryptogenic embolism in patients with
patent foramen ovale are administration of antithrombotic medications or percutaneous …

Background We conducted a systematic review and meta‐analysis of randomized controlled
trials (RCT s) comparing patent foramen ovale (PFO) closure, anticoagulation, and …

Background The prevalence of patent foramen ovale among patients with cryptogenic stroke
is higher than that in the general population. Closure with a percutaneous device is often …

Background Up to 40% of ischaemic strokes are cryptogenic. A strong association between
cryptogenic stroke and the prevalence of patent foramen ovale (PFO) suggests paradoxical …

Nearly one-half of patients with cryptogenic stroke have a patent foramen ovale (PFO). The
dilemma of whether to close these PFOs percutaneously, in an effort to reduce the risk of …

Background Whether closure of a patent foramen ovale reduces the risk of recurrence of
ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown …

Background: Patients with patent foramen ovale and cryptogenic stroke are at risk of
recurrence, but there are few data on strategies to prevent this. Methods: We studied 280 …

Objective To examine the relative impact of three management options in patients aged< 60
years with cryptogenic stroke and a patent foramen ovale (PFO): PFO closure plus …

A patent foramen ovale (PFO) is common and found in nearly 25% of healthy individuals.
The majority of patients with PFO remain asymptomatic and they are not at increased risk for …

Objectives: This study sought to perform a meta-analysis of randomized controlled trials
comparing device closure with medical therapy in the prevention of recurrent neurological …