Pulmonary infections due to Aspergillus fumigatus result from the development of a colony of
tightly associated hyphae in contact with the air, either in the alveoli (invasive aspergillosis) …

The fungal cell is surrounded by a cell wall that acts as a sieve and a reservoir for effector
molecules that play an active role during infection. This cell wall is essential for fungal …

Invasive pulmonary aspergillosis is acquired through inhalation of conidia. Little is known
about early interactions between Aspergillus fumigatus conidia and alveolar epithelial cells …

Over the past several decades, research on the synthesis and organization of the cell wall
polysaccharides of Aspergillus fumigatus has expanded our knowledge of this important …

Aspergillus species frequently colonize lower respiratory tracts and lungs with localized
underlying conditions (healed tuberculous cavity, cystic fibrosis, bronchiectasis, etc.) even in …

BACKGROUND: Aspergillus fumigatus is an opportunistic pathogen to which asthmatic
subjects are particularly susceptible. The ability of spores of A fumigatus to bind to …

Aspergillus fumigatus is an increasingly prevalent opportunistic fungal pathogen of various
immuno-compromised individuals. It has the ability to filament within the lungs forming …

Aspergillus colonization of the lower respiratory airways is common in normal people, and of
little clinical significance. However, in some patients, colonization is associated with severe …

Jean-Paul's research interest is focused on the analysis of the structure and biosynthesis of
the cell wall of Aspergillus fumigatus and its interaction with the host. The A. fumigatus …

Aspergillus fumigatus is the most prevalent airborne fungal pathogen responsible for fatal
invasive aspergillosis in immunocompromised patients. Upon arrival in the lung alveolus …