Spinal cord repair: from cells and tissue engineering to extracellular vesicles

S Guo, I Redenski, S Levenberg - Cells, 2021 - mdpi.com
Spinal cord injury (SCI) is a debilitating condition, often leading to severe motor, sensory, or
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …

Perspectives in the cell-based therapies of various aspects of the spinal cord injury-associated pathologies: Lessons from the animal models

M Zawadzka, A Kwaśniewska, K Miazga, U Sławińska - Cells, 2021 - mdpi.com
Traumatic injury of the spinal cord (SCI) is a devastating neurological condition often leading
to severe dysfunctions, therefore an improvement in clinical treatment for SCI patients is …

The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Multipotent mesenchymal stem cell-based therapies for spinal cord injury: current progress and future prospects

CW Zeng - Biology, 2023 - mdpi.com
Simple Summary Mesenchymal stem cells (MSCs) are a promising option for developing
new treatments for spinal cord injury (SCI). They can help repair damaged tissue, making …

Mesenchymal stem cell-derived exosomes: hope for spinal cord injury repair

Z Ren, Y Qi, S Sun, Y Tao, R Shi - Stem cells and development, 2020 - liebertpub.com
Spinal cord injury (SCI) is a devastating medical condition with profound social and
economic impacts. Although research is ongoing, current treatment options are limited and …

Biomaterial-supported cell transplantation treatments for spinal cord injury: challenges and perspectives

S Liu, T Schackel, N Weidner… - Frontiers in cellular …, 2018 - frontiersin.org
Spinal cord injury (SCI), resulting in para-and tetraplegia caused by the partial or complete
disruption of descending motor and ascending sensory neurons, represents a complex …

The combined strategy of mesenchymal stem cells and tissue-engineered scaffolds for spinal cord injury regeneration

P Bramanti, E Mazzon - … and Therapeutic Medicine, 2017 - spandidos-publications.com
Spinal cord injury (SCI) is a traumatic lesion that can result in the loss of motor or sensory
neurons. Stem cell (SC)‑based therapies have been demonstrated to promote neuronal …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: the development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

Current options for cell therapy in spinal cord injury

I Vismara, S Papa, F Rossi, G Forloni… - Trends in molecular …, 2017 - cell.com
Spinal cord injury (SCI) is a complex pathology that evolves after primary acute mechanical
injury, causing further damage to the spinal cord tissue that exacerbates clinical outcomes …

Regenerative medicine for the treatment of spinal cord injury: more than just promises?

AP Pêgo, S Kubinova, D Cizkova… - Journal of Cellular …, 2012 - Wiley Online Library
Spinal cord injury triggers a complex set of events that lead to tissue healing without the
restoration of normal function due to the poor regenerative capacity of the spinal cord …