Recently, the significantly higher incidence of Alzheimer's disease (AD) in women than in
men has been attributed to the loss of neuroprotective estrogen after menopause. Does …

Estrogen was shown to promote neuronal survival against several neurotoxic insults
including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen …

Alzheimer's disease (AD) is a well-studied neurodegenerative disorder; nevertheless,
significant therapeutic agents for the pharmacological treatment of this neuropathology are …

Epidemiological data have indicated that estrogen replacement therapy (ERT) can decrease
the risk of developing Alzheimer's disease (AD). Phytoestrogens have been proposed as …

Although favorable effects of estrogen replacement therapy on Alzheimer's disease on
postmenopausal women have been recognized, an associated increased incidence of …

Abstract Alzheimer's disease (AD), a massive challenge to global health, is featured with the
extracellular plaques made up of amyloid-β 42 (Aβ42) and the intracellular neurofibrillary …

Abstract Background Neurodegeneration in Alzheimer's disease is associated with
increased apoptosis and parallels increased levels of amyloid beta, which can induce …

Estrogen is neuroprotective against a variety of insults, including β-amyloid peptide (Aβ);
however, the underlying mechanism (s) is not fully understood. Here, we report that 17β …

Amyloid β-peptide (Aβ) has been implicated in the pathogenesis of AD. It can cause cell
death in AD by evoking a cascade of oxidative damage to neurons. So antioxidant …

Oestrogenic compounds have been postulated as neuroprotective agents. This prompted us
to investigate their mechanism action in neurons in primary culture. Cells were pretreated …