[HTML][HTML] Emerging NK cell therapies for cancer and the promise of next generation engineering of iPSC-derived NK cells

S Maddineni, JL Silberstein… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Adoptive cell therapy is a rapidly advancing approach to cancer immunotherapy that seeks
to facilitate antitumor responses by introducing potent effector cells into the tumor …

Natural killer cells in antitumour adoptive cell immunotherapy

TJ Laskowski, A Biederstädt, K Rezvani - Nature Reviews Cancer, 2022 - nature.com
Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with
intrinsic abilities to identify and eliminate virally infected cells and tumour cells. Possessing …

Next generation natural killer cells for cancer immunotherapy

F Rossi, N Fredericks, A Snowden… - Frontiers in …, 2022 - frontiersin.org
In recent years, immunotherapy for cancer has become mainstream with several products
now authorized for therapeutic use in the clinic and are becoming the standard of care for …

The application of natural killer cell immunotherapy for the treatment of cancer

K Rezvani, RH Rouce - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are essential components of the innate immune system and play a
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …

Next generation natural killer cells for cancer immunotherapy: the promise of genetic engineering

M Daher, K Rezvani - Current opinion in immunology, 2018 - Elsevier
Highlights•NK cells play a critical role in cancer immune surveillance.•NK cellular therapy is
safe but has some limitations.•Genetic engineering strategies are being employed to …

Arming immune cells for battle: A brief journey through the advancements of T and NK cell immunotherapy

P Wendel, LM Reindl, T Bexte, L Künnemeyer… - Cancers, 2021 - mdpi.com
Simple Summary This review is intended to provide an overview on the history and recent
advances of T cell and natural killer (NK) cell-based immunotherapy. While the thymus was …

[HTML][HTML] NK cell-based immunotherapies in cancer

MH Shin, J Kim, SA Lim, J Kim, SJ Kim, KM Lee - Immune network, 2020 - ncbi.nlm.nih.gov
With the development of technologies that can transform immune cells into therapeutic
modalities, immunotherapy has remarkably changed the current paradigm of cancer …

Exploring the NK cell platform for cancer immunotherapy

JA Myers, JS Miller - Nature reviews Clinical oncology, 2021 - nature.com
Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that are
capable of killing virally infected and/or cancerous cells. Nearly 20 years ago, NK cell …

NK cell-based immunotherapy for cancer

F Fang, W Xiao, Z Tian - Seminars in immunology, 2017 - Elsevier
Natural killer (NK) cells can induce an antigen-independent immune response against
malignant cells. A growing number of scientific reports and clinical studies have shown …

NK cell-based cancer immunotherapy: from basic biology to clinical development

S Liu, V Galat, Y Galat4, YKA Lee… - Journal of hematology & …, 2021 - Springer
Natural killer (NK) cell is a specialized immune effector cell type that plays a critical role in
immune activation against abnormal cells. Different from events required for T cell activation …