Pain is the leading cause of medical consultations and occurs in 50–70% of emergency
department visits. To date, several drugs have been used to manage pain. The clinical use …

Ketamine has been used as an anesthetic agent for over 50 years. At the upper end of the
dosing range, it displays dissociative anesthetic and amnestic effects, while at lower doses …

Objective: In the context of the current opioid epidemic, there has been a renewed interest in
the use of ketamine as an analgesic agent. Methods: We reviewed ketamine analgesia …

Since ketamine was approved by the FDA as an intravenous anesthetic, it has been in
clinical use for more than 50 years. Apart from its anesthetic effects, ketamine is one of the …

Background Few publications have addressed prehospital use of ketamine in analgesic
doses. We aimed to assess the effect and safety profile of ketamine compared with other …

Ketamine is a dissociative anaesthetic; its mechanism of action is primarily an antagonism of
the N-methyl-d-aspartate (NMDA) receptor. The role of ketamine, in particular in lower sub …

Ketamine is an anaesthetic drug with unique properties. Discovered in the 1960s, it is known
to produce a dissociative state with sedation, amnesia, and analgesia. It has relatively less …

An old anesthetic agent, ketamine is finding new use in lower doses for analgesic purposes.
There are concerns stemming from its potential side effects—specifically psychomimetic …

Abstract Purpose of Review In this article, we will review evidence for ketamine's role in
chronic pain and mental health conditions, its current legal status and abuse potential, and …

Background Subdissociative‐dose ketamine (SDDK) is used to treat acute pain. We sought
to determine if SDDK is effective in relieving acute exacerbations of chronic pain. Methods …