Colorectal cancer (CRC) is one type of tumor with the highest frequency and mortality
worldwide. Although current treatments increase patient survival, it is important to detect …

Pericytes are multipotent perivascular cells whose involvement in vasculature development
is well established. Evidences in the literature also suggest that pericytes display immune …

Pericytes are a type of mural cell located between the endothelial cells of capillaries and the
basement membrane, which function to regulate the capillary vasomotor and maintain …

The crosstalk between cancer cells and the tumor microenvironment has been implicated in
cancer progression and metastasis. Fibroblasts and immune cells are widely known to be …

Colorectal carcinoma (CRC) is a leading cause of cancer mortality. Tumorigenesis is a
dynamic process wherein cancer stem cells (CSCs) and their microenvironment promote …

Blood vessels consist of an inner endothelial cell layer lining the vessel wall and
perivascular pericytes, also known as mural cells, which envelop the vascular tube surface …

Cancer cells are embedded within the tumor microenvironment and interact dynamically
with its components during tumor progression. Understanding the molecular mechanisms by …

Pericytes (PCs), known as mural cells, play an important blood vessel (BV) supporting role
in regulating vascular stabilization, permeability and blood flow in microcirculation as well as …

Despite promising results in preclinical and clinical studies, the therapeutic efficacy of
antiangiogenic therapies has been restricted by a narrow focus on inhibiting the growth of …

Background: Pericytes are members of the tumor stroma; however, little is known about their
origin, function, or interaction with other tumor components. Emerging evidence suggest that …