[HTML][HTML] Organ-on-a-chip: Recent breakthroughs and future prospects

Q Wu, J Liu, X Wang, L Feng, J Wu, X Zhu… - Biomedical engineering …, 2020 - Springer
The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a
physiological organ biomimetic system built on a microfluidic chip. Through a combination of …

State of the art in integrated biosensors for organ-on-a-chip applications

Y Zhu, K Mandal, AL Hernandez, S Kawakita… - Current opinion in …, 2021 - Elsevier
Abstract Organ-on-a-chip (OoC) models are bioengineered tissue constructs integrated with
microfluidics that recapitulate the key features of the physiology of human organs and …

[HTML][HTML] Organ-on-a-chip: A survey of technical results and problems

AE Danku, EH Dulf, C Braicu, A Jurj… - … in Bioengineering and …, 2022 - frontiersin.org
Organ-on-a-chip (OoC), also known as micro physiological systems or 'tissue chips' have
attracted substantial interest in recent years due to their numerous applications, especially in …

[HTML][HTML] A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Advances in organ-on-a-chip engineering

B Zhang, A Korolj, BFL Lai, M Radisic - Nature Reviews Materials, 2018 - nature.com
Predicting the effects of drugs before human clinical trials is at the heart of drug screening
and discovery processes. The cost of drug discovery is steadily increasing owing to the …

[HTML][HTML] Microfluidic organ-on-a-chip system for disease modeling and drug development

Z Li, J Hui, P Yang, H Mao - Biosensors, 2022 - mdpi.com
An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering
to replicate the critical physiological environment and functions of the human organs …

Integrating organs-on-chips: multiplexing, scaling, vascularization, and innervation

DY Park, J Lee, JJ Chung, Y Jung, SH Kim - Trends in biotechnology, 2020 - cell.com
Organs-on-chips (OoCs) have attracted significant attention because they can be designed
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …

Physiologically relevant organs on chips

K Yum, SG Hong, KE Healy, LP Lee - Biotechnology journal, 2014 - Wiley Online Library
Recent advances in integrating microengineering and tissue engineering have generated
promising microengineered physiological models for experimental medicine and …

Organ-on-a-chip engineering: Toward bridging the gap between lab and industry

Q Ramadan, M Zourob - Biomicrofluidics, 2020 - pubs.aip.org
Organ-on-a-chip (OOC) is a very ambitious emerging technology with a high potential to
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …

Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies

S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …