[HTML][HTML] The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation

SM Kousik, TC Napier, PM Carvey - Frontiers in pharmacology, 2012 - frontiersin.org
The blood brain barrier (BBB) is a highly dynamic interface between the central nervous
system (CNS) and periphery. The BBB is comprised of a number of components and is part …

Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress

RK Sajja, S Rahman, L Cucullo - Journal of Cerebral Blood …, 2016 - journals.sagepub.com
Psychostimulants and nicotine are the most widely abused drugs with a detrimental impact
on public health globally. While the long-term neurobehavioral deficits and synaptic …

[HTML][HTML] Effects of drugs of abuse on the blood-brain barrier: a brief overview

E Pimentel, K Sivalingam, M Doke… - Frontiers in …, 2020 - frontiersin.org
The use of psychostimulants and alcohol disrupts blood-brain barrier (BBB) integrity,
resulting in alterations to cellular function, and contributes to neurotoxicity. The BBB is the …

Alteration of blood-brain barrier function by methamphetamine and cocaine

JB Dietrich - Cell and tissue research, 2009 - Springer
The integrity of the blood-brain barrier (BBB) plays an important role in maintaining a safe
neural microenvironment in the brain. Loss of BBB integrity has been recognized as a major …

Current preclinical studies on neuroinflammation and changes in blood–brain barrier integrity by MDMA and methamphetamine

E O'Shea, A Urrutia, AR Green, MI Colado - Neuropharmacology, 2014 - Elsevier
The blood–brain barrier (BBB) is essential in the maintenance of brain homeostasis both by
preserving normal brain functioning and also by protecting the brain from exposure to a …

Methamphetamine disrupts blood–brain barrier function by induction of oxidative stress in brain endothelial cells

SH Ramirez, R Potula, S Fan, T Eidem… - Journal of Cerebral …, 2009 - journals.sagepub.com
Methamphetamine (METH), a potent stimulant with strong euphoric properties, has a high
abuse liability and long-lasting neurotoxic effects. Recent studies in animal models have …

The TNF-α/Nf-κB Signaling Pathway has a Key Role in Methamphetamine–Induced Blood–Brain Barrier Dysfunction

V Coelho-Santos, RA Leitão… - Journal of Cerebral …, 2015 - journals.sagepub.com
Methamphetamine (METH) is a psychostimulant that causes neurologic and psychiatric
abnormalities. Recent studies have suggested that its neurotoxicity may also result from its …

The impact of substance abuse on HIV-mediated neuropathogenesis in the current ART era

V Chilunda, TM Calderon, P Martinez-Aguado… - Brain research, 2019 - Elsevier
Approximately 37 million people worldwide are infected with human immunodeficiency virus
(HIV). One highly significant complication of HIV infection is the development of HIV …

Blood-brain barrier regulation in psychiatric disorders

J Kealy, C Greene, M Campbell - Neuroscience letters, 2020 - Elsevier
The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …

Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier

AP Silva, T Martins, S Baptista… - Current drug abuse …, 2010 - ingentaconnect.com
Over the course of the 20th century, it became increasingly clear that amphetamine-like
psychostimulants carried serious abuse liability that has resulted in sociological use patterns …