Distinguishing Cushing's disease from the ectopic ACTH syndrome: Needles in a haystack or hiding in plain sight?

AR Hayes, AB Grossman - Journal of Neuroendocrinology, 2022 - Wiley Online Library
In the context of ACTH‐dependent Cushing's syndrome, ectopic ACTH secretion from a
neuroendocrine tumour is not uncommon, and needs to be carefully differentiated from …

Ectopic ACTH-secreting syndrome: a single center experience report with a high prevalence of occult tumor

I Hernandez, AL Espinosa-de-los-Monteros… - Archives of Medical …, 2006 - Elsevier
BACKGROUND: Differentiation between the two forms of ACTH-dependent Cushing's
syndrome is a challenging task. Although the majority of these cases will be diagnosed as …

Ectopic ACTH syndrome

AM Isidori, GA Kaltsas, AB Grossman - Pituitary Today: Molecular …, 2006 - karger.com
Ectopic adrenocorticotropin secretion (EAS) accounts for 10-15% of cases of Cushing's
syndrome and comprises a spectrum of tumours from undetectable isolated lesions to …

The ectopic ACTH syndrome

KI Alexandraki, AB Grossman - Reviews in endocrine and metabolic …, 2010 - Springer
Ectopic Cushing's syndrome usually relates to the ectopic ACTH syndrome (EAS) and
represents∼ 20% of ACTH-dependent and∼ 10% of all types of Cushing's syndrome (CS) …

Diagnosis and management of ACTH‐dependent Cushing's syndrome: comparison of the features in ectopic and pituitary ACTH production

TA Howlett, PL Drury, L Perry, I Doniach… - Clinical …, 1986 - Wiley Online Library
The clinical features, diagnosis and management of 16 consecutive patients with ectopic
ACTH production are described and biochemical data are compared with those of 48 …

Ectopic ACTH syndrome of different origin—diagnostic approach and clinical outcome. Experience of one Clinical Centre

JE Paleń-Tytko, EM Przybylik-Mazurek, EJ Rzepka… - PLoS …, 2020 - journals.plos.org
Purpose Ectopic Cushing Syndrome (EAS) is a rare condition responsible for about 5–20%
of all Cushing syndrome cases. It increases the mortality of affected patients thus finding and …

[HTML][HTML] Imaging in Cushing's syndrome

A Sahdev, RH Reznek, J Evanson… - Arquivos Brasileiros de …, 2007 - SciELO Brasil
Once the diagnosis of Cushing's syndrome (CS) has been established, the main step is to
differentiate between ACTH dependent and independent disease. In adults, 80% of CS is …

Diagnostic workup of Cushing's syndrome

M Balomenaki, D Margaritopoulos… - Journal of …, 2022 - Wiley Online Library
Cushing's syndrome (CS) is a rare but detrimental endocrine disorder. Early diagnosis and
prompt treatment are essential since the duration of hypercortisolism has an adverse impact …

Differential diagnosis and imaging in Cushing's syndrome

JR Lindsay, LK Nieman - Endocrinology and Metabolism …, 2005 - endo.theclinics.com
Establishing the cause of Cushing's syndrome (CS) should be undertaken only after the
clinical and biochemical diagnosis has been confirmed. This process of differential …

Cushing's disease

X Bertagna, L Guignat, L Groussin… - Best Practice & Research …, 2009 - Elsevier
Cushing's syndrome refers to the clinical manifestations induced by chronic exposure to
excess glucocorticoids. There are three pathological conditions that can result in the chronic …