[PDF][PDF] Role of leptin in immunity

QL Lam, L Lu - Cell Mol Immunol, 2007 - cmi.ustc.edu.cn
Leptin, a protein hormone produced by the adipocytes, has long been recognized to
regulate metabolism, neuroendorine and other physiological functions. Early findings of …

Leptin regulation of immune responses

C Naylor, WA Petri - Trends in molecular medicine, 2016 - cell.com
Leptin is a regulatory hormone with multiple roles in the immune system. We favor the
concept that leptin signaling 'licenses' various immune cells to engage in immune responses …

The weight of leptin in immunity

AL Cava, G Matarese - Nature Reviews Immunology, 2004 - nature.com
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. As a hormone, leptin regulates food intake and …

Leptin as an immunomodulator

C Procaccini, E Jirillo, G Matarese - Molecular aspects of medicine, 2012 - Elsevier
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. In humans, leptin influences energy homeostasis …

Unraveling the multiple roles of leptin in inflammation and autoimmunity

A La Cava, C Alviggi, G Matarese - Journal of molecular medicine, 2004 - Springer
Initially described as an antiobesity hormone, leptin has subsequently been shown also to
influence hematopoiesis, thermogenesis, reproduction, angiogenesis, and immune …

Leptin beyond body weight regulation—current concepts concerning its role in immune function and inflammation

R Lago, R Gomez, F Lago, J Gómez-Reino… - Cellular immunology, 2008 - Elsevier
Leptin, a 16kDa non-glycosylated polypeptide produced primarily by adipocytes and
released into the systemic circulation, exerts a multitude of regulatory functions including …

Leptin in immunology

G Matarese, S Moschos… - The Journal of Immunology, 2005 - journals.aai.org
Leptin is an adipokine which conveys information on energy availability. In humans, leptin
influences energy homeostasis and regulates neuroendocrine function primarily in states of …

Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action

V Sanchez-Margalet, C Martin-Romero… - Clinical & …, 2003 - academic.oup.com
Leptin is a an adipocyte-secreted hormone that regulates weight centrally. However, the
leptin receptor is expressed not only in the central nervous system, but also in peripheral …

[HTML][HTML] Leptin, from fat to inflammation: old questions and new insights

M Otero, R Lago, F Lago, FF Casanueva, C Dieguez… - FEBS letters, 2005 - Elsevier
Leptin is 16 kDa adipokine that links nutritional status with neuroendocrine and immune
functions. Initially thought to be a satiety factor that regulates body weight by inhibiting food …

Leptin in autoimmune diseases

C Procaccini, V Pucino, CS Mantzoros, G Matarese - Metabolism, 2015 - Elsevier
The past twenty years of research on leptin has provided crucial information on the link
between metabolic state and immune system function. Adipocytes influence not only the …