[HTML][HTML] Pancreatic regional blood flow links the endocrine and exocrine diseases

AA Rizk, MP Dybala, KC Rodriguez… - The Journal of …, 2023 - Am Soc Clin Investig
An increasing number of studies have demonstrated that disease states of the endocrine or
exocrine pancreas aggravate one another, which implies bidirectional blood flow between …

Local dialogues between the endocrine and exocrine cells in the pancreas

M Slak Rupnik, M Hara - Diabetes, 2024 - Am Diabetes Assoc
For many years, it has been taught in medical textbooks that the endocrine and exocrine
parts of the pancreas have separate blood supplies that do not mix. Therefore, they have …

Integrated pancreatic blood flow: bidirectional microcirculation between endocrine and exocrine pancreas

MP Dybala, A Kuznetsov, M Motobu… - Diabetes, 2020 - Am Diabetes Assoc
The pancreatic islet is a highly vascularized endocrine micro-organ. The unique architecture
of rodent islets, a so-called core-mantle arrangement seen in two-dimensional images, led …

Implications of integrated pancreatic microcirculation: crosstalk between endocrine and exocrine compartments

MP Dybala, LR Gebien, ME Reyna, Y Yu, M Hara - Diabetes, 2020 - Am Diabetes Assoc
The endocrine and exocrine pancreas have been studied separately by endocrinologists
and gastroenterologists as two organ systems. The pancreatic islet, consisting of 1–2 …

[HTML][HTML] Blood flow in the pancreatic islet: not so isolated anymore

J Almaça, A Caicedo - Diabetes, 2020 - ncbi.nlm.nih.gov
The pancreatic islet is a highly vascularized endocrine mini-organ that depends on blood
supply to function efficiently. As blood flows through islet capillaries reaching different …

Pancreatic blood flow with special emphasis on blood perfusion of the islets of Langerhans

L Jansson, PO Carlsson - Comprehensive Physiology, 2011 - Wiley Online Library
The pancreatic islets are more richly vascularized than the exocrine pancreas, and possess
a 5‐to 10‐fold higher basal and stimulated blood flow, which is separately regulated. This is …

[引用][C] The regulation of pancreatic islet blood flow

L Jansson - Diabetes/metabolism reviews, 1994 - Wiley Online Library
The vascular supply is of crucial importance for endocrine organs since the
microvasculature, in addition to supplying oxygen and nutrients, is initially responsible for …

[HTML][HTML] Functional characterization of the human islet microvasculature using living pancreas slices

L Mateus Gonçalves, J Almaça - Frontiers in endocrinology, 2021 - frontiersin.org
Pancreatic islets are clusters of endocrine cells that secrete different hormones to regulate
blood glucose levels. Efficient hormone secretion requires a close interaction of endocrine …

[HTML][HTML] Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets

LR Nyman, KS Wells, WS Head… - The Journal of …, 2008 - Am Soc Clin Investig
The pancreatic islets of Langerhans are highly vascularized micro-organs that play a key
role in the regulation of blood glucose homeostasis. The specific arrangement of endocrine …

[HTML][HTML] Structure of islets and vascular relationship to the exocrine pancreas

Y El-Gohary, G Gittes - Pancreapedia: The Exocrine Pancreas …, 2018 - pancreapedia.org
The pancreas is a retroperitoneal organ with its function being dictated by the possession of
two morphologically distinct tissues, the exocrine and endocrine pancreas. The endocrine …