Newborn neurons in the adult hippocampus are regulated by many intrinsic and extrinsic
cues. It is well accepted that elevated glucocorticoid levels lead to downregulation of adult …

Coping with stress is fundamental for mental health, but understanding of the molecular
neurobiology of stress is still in its infancy. Adult neurogenesis is well known to be regulated …

Adult hippocampal neurogenesis in the developmental process of generating and
integrating new neurons in the hippocampus during adulthood and is a unique form of …

Adult neurogenesis, the birth of new neurons in the mature brain, has attracted considerable
attention in the last decade. One of the earliest identified and most profound factors that …

Recent research suggests an involvement of hippocampal neurogenesis in behavioral
effects of antidepressants. However, the precise mechanisms through which newborn …

There is a growing appreciation that adult hippocampal neurogenesis plays a role in
emotional and cognitive processes related to psychiatric disorders. Although many studies …

Chronic stress and depression are associated with decreased levels of hippocampal
neurogenesis. On the other hand, antidepressants as well as environmental enrichment may …

Adolescence represents a critical period for brain and behavioural health and characterised
by the onset of mood, psychotic and anxiety disorders. In rodents, neurogenesis is very …

Recent evidence implicates adult hippocampal neurogenesis in regulating behavioral and
physiologic responses to stress. Hippocampal neurogenesis occurs across the lifespan …

Whereas genetic factors contribute crucially to brain function, early-life events, including
stress, exert long-lasting influence on neuronal function. Here, we focus on the …