Ovarian cancer immunotherapy: preclinical models and emerging therapeutics

CW McCloskey, GM Rodriguez, KJC Galpin… - Cancers, 2018 - mdpi.com
Immunotherapy has emerged as one of the most promising approaches for ovarian cancer
treatment. The tumor microenvironment (TME) is a key factor to consider when stimulating …

Combination therapy targeting both innate and adaptive immunity improves survival in a pre-clinical model of ovarian cancer

CA Hartl, A Bertschi, RB Puerto, C Andresen… - … for ImmunoTherapy of …, 2019 - Springer
Background Despite major advancements in immunotherapy among a number of solid
tumors, response rates among ovarian cancer patients remain modest. Standard treatment …

The tumor immune profile of murine ovarian cancer models: an essential tool for ovarian cancer immunotherapy research

GM Rodriguez, KJC Galpin, DP Cook… - Cancer research …, 2022 - AACR
Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer with an imperative
need for new treatments. Immunotherapy has had marked success in some cancer types; …

[HTML][HTML] Immunotherapy for ovarian cancer: what's next?

LE Kandalaft, DJ Powell Jr, N Singh… - Journal of Clinical …, 2011 - ncbi.nlm.nih.gov
In the past decade, we have witnessed important gains in the treatment of ovarian cancer;
however, additional advances are required to reduce mortality. With compelling evidence …

RETRACTED ARTICLE: Targeted immune therapy of ovarian cancer

KL Knutson, L Karyampudi, P Lamichhane… - Cancer and Metastasis …, 2015 - Springer
Clinical outcomes, such as recurrence-free survival and overall survival, in ovarian cancer
are quite variable, independent of common characteristics such as stage, response to …

Immunologic approaches to ovarian cancer treatment

P Sabbatini, K Odunsi - Journal of clinical oncology, 2007 - ascopubs.org
The clinical course of ovarian cancer is often marked by periods of relapse and remission
until chemotherapy resistance develops. Patients in remission with minimal disease burdens …

[HTML][HTML] Driving immune responses in the ovarian tumor microenvironment

F Ning, CB Cole, CM Annunziata - Frontiers in Oncology, 2021 - frontiersin.org
Ovarian cancer is the leading cause of death among gynecological neoplasms, with an
estimated 14,000 deaths in 2019. First-line treatment options center around a taxane and …

Immunity and immune suppression in human ovarian cancer

CC Preston, EL Goode, LC Hartmann, KR Kalli… - …, 2011 - Taylor & Francis
Clinical outcomes in ovarian cancer are heterogeneous, independent of common features
such as stage, response to therapy and grade. This disparity in outcomes warrants further …

The immune system in the pathogenesis of ovarian cancer

B Charbonneau, EL Goode, KR Kalli… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Clinical outcomes in ovarian cancer are heterogeneous even when considering common
features such as stage, response to therapy, and grade. This disparity in outcomes warrants …

Immunotherapy for ovarian cancer: recent advances and perspectives

E Zsiros, J Tanyi, K Balint… - Current opinion in …, 2014 - journals.lww.com
Dramatic increase in the number of immunotherapy clinical trials was seen in the past
decade with promising results in enhancing antitumor immune response and cancer vaccine …