The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer
FE Lennon, T Mirzapoiazova, B Mambetsariev… - PloS one, 2014 - journals.plos.org
Recent epidemiologic studies implying differences in cancer recurrence based on
anesthetic regimens raise the possibility that the mu opioid receptor (MOR) can influence …
anesthetic regimens raise the possibility that the mu opioid receptor (MOR) can influence …
The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation
BACKGROUND: The possibility that μ opioid agonists can influence cancer recurrence is a
subject of recent interest. Epidemiologic studies suggested that there were differences in …
subject of recent interest. Epidemiologic studies suggested that there were differences in …
Overexpression of the μ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis
FE Lennon, T Mirzapoiazova… - The Journal of the …, 2012 - pubs.asahq.org
Background Recent epidemiologic studies suggesting that there were differences in cancer
recurrence contingent on anesthetic regimens have raised the possibility that μ-opioid …
recurrence contingent on anesthetic regimens have raised the possibility that μ-opioid …
Morphine suppresses lung cancer cell proliferation through the interaction with opioid growth factor receptor: an in vitro and human lung tissue study
JY Kim, HJ Ahn, JK Kim, J Kim, SH Lee… - Anesthesia & …, 2016 - journals.lww.com
BACKGROUND: There have been inconsistent reports on whether opioids promote or inhibit
lung cancer growth. In this study, we suggest that opioid growth factor receptor (OGFR), a …
lung cancer growth. In this study, we suggest that opioid growth factor receptor (OGFR), a …
Effect of perioperative opioids on cancer recurrence: a hypothesis
PA Singleton, J Moss - Future oncology, 2010 - Taylor & Francis
The possibility that anesthetic drugs can influence cancer recurrence rate is a subject of
recent interest. Based on early in vitro data demonstrating opiates on breast cancer …
recent interest. Based on early in vitro data demonstrating opiates on breast cancer …
Increased μ-opioid receptor expression in metastatic lung cancer
PA Singleton, T Mirzapoiazova, R Hasina… - British journal of …, 2014 - academic.oup.com
Background We and others have previously demonstrated that the μ-opioid receptor (MOR)
is overexpressed in several human malignancies. There is a seven-fold increase in MOR in …
is overexpressed in several human malignancies. There is a seven-fold increase in MOR in …
Morphine-induced epidermal growth factor pathway activation in non–small cell lung cancer
N Fujioka, J Nguyen, C Chen, Y Li, T Pasrija… - Anesthesia & …, 2011 - journals.lww.com
BACKGROUND: Epidermal growth factor receptor (EGFR) is coactivated by the μ-opioid
receptor (MOR), expressed on non–small cell lung cancer (NSCLC) cells and human lung …
receptor (MOR), expressed on non–small cell lung cancer (NSCLC) cells and human lung …
Association of mu-opioid receptor expression with lymph node metastasis in esophageal squamous cell carcinoma
YF Zhang, QX Xu, LD Liao, XE Xu, JY Wu… - Diseases of the …, 2015 - academic.oup.com
The mu-opioid receptor (MOR), a membrane-bound G protein-coupled receptor, is the main
target for opioids in the nervous system. MOR1 has been found in several types of cancer …
target for opioids in the nervous system. MOR1 has been found in several types of cancer …
[HTML][HTML] The mu-opioid receptor is a molecular marker for poor prognosis in hepatocellular carcinoma and represents a potential therapeutic target
DT Chen, JH Pan, YH Chen, W Xing, Y Yan… - British journal of …, 2019 - Elsevier
Background Opioid receptors are implicated in cancer progression and long-term patient
outcomes. However, the prognostic significance, underlying mechanisms, and therapeutic …
outcomes. However, the prognostic significance, underlying mechanisms, and therapeutic …
The μ-opioid receptor (MOR) promotes tumor initiation in hepatocellular carcinoma
Y Li, G Li, T Tao, X Kang, C Liu, X Zhang, C Wang, C Li… - Cancer Letters, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer. Anesthetic
regimens possibly influence cancer development. Exploration of novel, effective targets for …
regimens possibly influence cancer development. Exploration of novel, effective targets for …
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