The impact of nintedanib and pirfenidone on lung function and survival in patients with idiopathic pulmonary fibrosis in real-life setting

G Santos, A Fabiano, PC Mota, I Rodrigues… - Pulmonary …, 2023 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, fibrosing interstitial pneumonia
of unknown cause that is associated with radiological and/or histological features of usual …

Impact of reduction in antifibrotic treatment on mortality in idiopathic pulmonary fibrosis

S Porse, N Hoyer, SB Shaker - Respiratory medicine, 2022 - Elsevier
Introduction Idiopathic pulmonary fibrosis (IPF) is a severe interstitial lung disease for which
two effective antifibrotics, nintedanib and pirfenidone, are available. However, many patients …

[HTML][HTML] Long-term follow-up of patients with idiopathic pulmonary fibrosis treated with pirfenidone or nintedanib: a real-life comparison study

P Cameli, RM Refini, L Bergantini… - Frontiers in Molecular …, 2020 - frontiersin.org
Background Pirfenidone and nintedanib are the sole pharmacological therapies currently
approved for idiopathic pulmonary fibrosis (IPF). Limited comparison data is available in …

Real-world retrospective observational study exploring the effectiveness and safety of antifibrotics in idiopathic pulmonary fibrosis

WA Wright, LE Crowley, D Parekh… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Background Pirfenidone and nintedanib are the only disease-modifying treatments available
for idiopathic pulmonary fibrosis (IPF). Our aim was to test their effectiveness and safety in …

A real-life multicenter national study on nintedanib in severe idiopathic pulmonary fibrosis

S Harari, A Caminati, V Poletti, M Confalonieri… - Respiration, 2018 - karger.com
Background: Two therapeutic options are currently available for patients with mild-to-
moderate idiopathic pulmonary fibrosis (IPF): pirfenidone and nintedanib. To date, there is …

Tolerability and efficacy of second-line antifibrotics in patients with idiopathic pulmonary fibrosis

A Cilli, F Uzer, C Sevinç, F Coşkun, A Ursavaş… - Pulmonary …, 2021 - Elsevier
Background The antifibrotic drugs nintedanib and pirfenidone reduce disease progression
in idiopathic pulmonary fibrosis (IPF) and have also shown to improve survival. Switching …

[HTML][HTML] Pirfenidone and Nintedanib in idiopathic pulmonary fibrosis: Real-life experience in an Italian referral centre

E Bargagli, C Piccioli, E Rosi, E Torricelli, L Turi… - Pulmonology, 2019 - Elsevier
Background Idiopathic pulmonary fibrosis has a median survival time after diagnosis of 2–5
years. The main goal of treating IPF is to stabilize or reduce the rate of disease progression …

[HTML][HTML] Real-life comparison of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis: A 24-month assessment

S Cerri, M Monari, A Guerrieri, P Donatelli, I Bassi… - Respiratory …, 2019 - Elsevier
Background Real-life data on the use of pirfenidone and nintedanib to treat patients with
idiopathic pulmonary fibrosis (IPF) are still scarce. Methods We compared the efficacy of …

[HTML][HTML] Idiopathic pulmonary fibrosis (IPF): an overview

SL Barratt, A Creamer, C Hayton… - Journal of clinical …, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic,
progressive scarring of the lungs and the pathological hallmark of usual interstitial …

[HTML][HTML] The effect of nintedanib on lung functions and survival in idiopathic pulmonary fibrosis: real-life analysis of the Czech EMPIRE registry

M Štefániková, M Doubková, P Ovesná… - BMC Pulmonary …, 2023 - Springer
Introduction The antifibrotic drug nintedanib is used for the treatment of idiopathic pulmonary
fibrosis (IPF). We analysed the effect of nintedanib on antifibrotic treatment outcome in real …