[HTML][HTML] The role of lipoxidation in the pathogenesis of diabetic retinopathy

J Augustine, EP Troendle, P Barabas… - Frontiers in …, 2021 - frontiersin.org
Lipids can undergo modification as a result of interaction with reactive oxygen species
(ROS). For example, lipid peroxidation results in the production of a wide variety of highly …

[HTML][HTML] Oxidative stress and its regulation in diabetic retinopathy

CD Haydinger, GF Oliver, LM Ashander, JR Smith - Antioxidants, 2023 - mdpi.com
Diabetic retinopathy is the retinal disease associated with hyperglycemia in patients who
suffer from type 1 or type 2 diabetes. It includes maculopathy, involving the central retina and …

Advanced glycation and advanced lipoxidation: possible role in initiation and progression of diabetic retinopathy

AW Stitt, N Frizzell, SR Thorpe - Current pharmaceutical design, 2004 - ingentaconnect.com
Diabetic retinopathy remains the most common microvascular complication suffered by
diabetic patients and is the leading cause of registerable blindness in the working …

Diabetic retinopathy: important biochemical alterations and the main treatment strategies

AS ValdezGuerrero, JC Quintana-Pérez… - Canadian Journal of …, 2021 - Elsevier
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by impaired glucose
homeostasis, insulin resistance and hyperglycemia. Among its serious multisystemic …

[HTML][HTML] Molecular mechanisms of diabetic retinopathy: potential therapeutic targets

M Coucha, SL Elshaer, WS Eldahshan… - Middle East African …, 2015 - journals.lww.com
Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults in United
States. Research indicates an association between oxidative stress and the development of …

Therapeutic potential of anti-oxidants and diabetic retinopathy

RA Kowluru, A Kennedy - Expert opinion on investigational drugs, 2001 - Taylor & Francis
Retinopathy, a severely disabling complication of diabetes mellitus, is today the leading
cause of acquired blindness among young adults in developed countries. Good glycaemic …

Antioxidants and diabetic retinopathy

M Williams, RE Hogg, U Chakravarthy - Current diabetes reports, 2013 - Springer
The biochemical perturbations in diabetes mellitus (DM) create the conditions for the
production of free radicals, the consequence of which is increased oxidative stress …

Perturbed biochemical pathways and associated oxidative stress lead to vascular dysfunctions in diabetic retinopathy

N Mahajan, P Arora, R Sandhir - Oxidative medicine and …, 2019 - Wiley Online Library
Diabetic retinopathy (DR) is a vascular insult that accompanies the hyperglycemic state.
Retinal vasculature holds a pivotal role in maintaining the integrity of the retina, and any …

Oxidative stress: implications for the development of diabetic retinopathy and antioxidant therapeutic perspectives

Y Wu, L Tang, B Chen - Oxidative medicine and cellular …, 2014 - Wiley Online Library
In recent decades, localized tissue oxidative stress has been implicated as a key component
in the development of diabetic retinopathy (DR). Increasing evidence shows that oxidative …

Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives

SA Madsen-Bouterse, RA Kowluru - Reviews in Endocrine and Metabolic …, 2008 - Springer
Retinopathy is one of the most severe ocular complications of diabetes and is a leading
cause of acquired blindness in young adults. The cellular components of the retina are …