Mammalian carboxylesterases (CESs) are essential members of serine esterase hydrolase
superfamily, which are widely distributed in many tissues including liver, intestine, lung and …

As the most important members of serine esterase hydrolase superfamily, mammalian
carboxylesterases (CESs) are widely distributed in various tissues like liver, intestine, lung …

Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Abstract Carboxylesterase 2 (CES2) is a serine-type hydrolase that plays important roles in
xenobiotic detoxification and lipid metabolism. Its abnormal expression is highly associated …

Human carboxylesterases (CESs) are serine hydrolases that are responsible for the phase I
metabolism of an assortment of ester, amide, thioester, carbonate, and carbamate …

Abstract Carboxylesterase 1 (CES1), one of the most abundant serine hydrolases in
mammals, has drawn much attentions in recent years, owing to this enzyme involves in …

Rational design of practical probes with excellent specificity and improved optical properties
for a particular enzyme is always a big challenge. Herein, a practical and highly specific …

An aggregation-induced emission (AIE) fluorescent protein chromophore-based probe (CBZ-
FP) for detection of human carboxylesterases (CESs) was designed and synthesized. CBZ …

Carboxylesterases (CESs) play major roles in catalyzing the hydrolysis of a wide range of
ester-and amide-containing compounds. CESs dominate both the biotransformation of …

A novel ratiometric fluorescent probe derived from 2-(2′-hydroxy-3′-methoxyphenyl)
benzothiazole (HMBT) for human carboxylesterase 1 (hCES1) has been synthesized and …