High-throughput screening paradigms in ecotoxicity testing: Emerging prospects and ongoing challenges

D Wlodkowic, M Jansen - Chemosphere, 2022 - Elsevier
The rapidly increasing number of new production chemicals coupled with stringent
implementation of global chemical management programs necessities a paradigm shift …

Ecotoxicology goes on a chip: embracing miniaturized bioanalysis in aquatic risk assessment

O Campana, D Wlodkowic - Environmental science & technology, 2018 - ACS Publications
Biological and environmental sciences are, more than ever, becoming highly dependent on
technological and multidisciplinary approaches that warrant advanced analytical …

[图书][B] Biochemical ecotoxicology: principles and methods

F Gagné - 2014 - books.google.com
Biochemical Ecotoxicology: Principles and Methods presents practical approaches to
biochemical ecotoxicology experiments for environmental protection and conservation. With …

The undiscovered country: Ecotoxicology meets microfluidics

O Campana, D Wlodkowic - Sensors and Actuators B: Chemical, 2018 - Elsevier
Abstract Microfluidic Lab-on-a-Chip (LOC) technologies offer tremendous miniaturization
capabilities and enable innovative ways of performing biotests without the need for …

Big data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicants

H Zhu, J Zhang, MT Kim, A Boison… - Chemical research in …, 2014 - ACS Publications
High-throughput screening (HTS) assays that measure the in vitro toxicity of environmental
compounds have been widely applied as an alternative to in vivo animal tests of chemical …

Ecotoxicological risk assessment using DNA chips and cellular reporters

J Robbens, K van der Ven, M Maras, R Blust… - Trends in …, 2007 - cell.com
Ecotoxicological risk assessment has long been based on (acute) effective concentration
and lethal concentration (EC/LC50) endpoints in organisms from different trophic levels …

Toxicity testing in the 21st century: implications for human health risk assessment

D Krewski, ME Andersen, E Mantus… - Risk Analysis: An …, 2009 - Wiley Online Library
At the request of the Environmental Protection Agency, the National Research Council
(NRC) recently completed a major report entitled Toxicity Testing in the 21st Century: A …

[图书][B] Toxicity testing in the 21st century: a vision and a strategy

National Research Council, Division on Earth… - 2007 - books.google.com
Advances in molecular biology and toxicology are paving the way for major improvements in
the evaluation of the hazards posed by the large number of chemicals found at low levels in …

[图书][B] Microscale testing in aquatic toxicology: advances, techniques, and practice

PG Wells, K Lee, C Blaise - 2018 - books.google.com
Bioassays are among the ecotoxicologist's most effective weapons in the evaluation of water
quality and the assessment of ecological impacts of effluents, chemicals, discharges, and …

Analytical chemistry and ecotoxicology—Tasks, needs and trends

RIL Eggen, MJF Suter - Journal of Toxicology and Environmental …, 2007 - Taylor & Francis
Thousands of synthetic chemicals are continuously released into the environment, where
they have the potential to produce adverse effects on ecosystems, even at low …