Results of the European Group for the Study of Resistant Depression (GSRD)—basis for further research and clinical practice

L Bartova, M Dold, A Kautzky, C Fabbri… - The World Journal of …, 2019 - Taylor & Francis
Objectives: The overview outlines two decades of research from the European Group for the
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …

Diagnosis and definition of treatment-resistant depression

M Fava - Biological psychiatry, 2003 - Elsevier
Treatment-resistant depression (TRD) typically refers to inadequate response to at least one
antidepressant trial of adequate doses and duration. TRD is a relatively common occurrence …

Clinical factors predicting treatment resistant depression: affirmative results from the European multicenter study

A Kautzky, M Dold, L Bartova, M Spies… - Acta Psychiatrica …, 2019 - Wiley Online Library
Objectives Clinical variables were investigated in the 'treatment resistant depression (TRD)‐
III'sample to replicate earlier findings by the European research consortium 'Group for the …

European Group for the Study of Resistant Depression (GSRD)—where have we gone so far: review of clinical and genetic findings

A Schosser, A Serretti, D Souery, J Mendlewicz… - European …, 2012 - Elsevier
The primary objective of this review is to give an overview of the main findings of the
European multicenter project “Patterns of Treatment Resistance and Switching Strategies in …

Treatment resistant depression: methodological overview and operational criteria

D Souery, J Amsterdam, C De Montigny… - European …, 1999 - Elsevier
A wide variety of definitions are used for Treatment Resistant Depression (TRD), considering
various criteria and different concepts. Some of the key issues are: the diagnosis, the …

The impact of (the concept of) treatment-resistant depression: an opinion review

K Demyttenaere, Z Van Duppen - International Journal of …, 2019 - academic.oup.com
Abstract Treatment-resistant depression refers to major depressive disorder, treatment of the
disorder, and failure to obtain an “acceptable” outcome. Regarding the disorder, the …

Socio-demographic and clinical predictors of treatment resistant depression: a prospective European multicenter study

M Balestri, R Calati, D Souery, A Kautzky… - Journal of affective …, 2016 - Elsevier
Background Few studies investigated socio-demographic and clinical predictors of non
response and remission in treatment resistant depression (TRD) in the case of failure of …

A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough?

S Dodd, M Bauer, AF Carvalho, H Eyre… - The World Journal of …, 2021 - Taylor & Francis
Background Major depressive disorder is a common, recurrent, disabling and costly disorder
that is often severe and/or chronic, and for which non-remission on guideline concordant first …

Treatment-resistant depression

D Souery, GI Papakostas, MH Trivedi - Journal of Clinical …, 2006 - psychiatrist.com
Treatment-resistant depression (TRD) is a common clinical occurrence among patients
treated for major depressive disorder. However, a clear consensus regarding the criteria …

Is treatment-resistant depression a unique subtype of depression?

A Fagiolini, DJ Kupfer - Biological Psychiatry, 2003 - Elsevier
Treatment-resistant depression (TRD) continues to represent a major challenge for treating
clinicians. This report reviews the relevant literature to evaluate whether TRD can be …