The expanding use of genomic technologies encompasses all phases of life, from the
embryo to the elderly, and even the posthumous phase. In this paper, we present the …

The integration of new genetic technologies into clinical practice holds great promise for the
personalization of medical care, particularly the use of large-scale DNA sequencing for …

With the human genome project running from 1989 until its completion in 2003, and the
incredible advances in sequencing technology and in bioinformatics during the last decade …

The collection and use of human genetic data raise important ethical questions about how to
balance individual autonomy and privacy with the potential for public good. The proliferation …

Genomic science and associated technologies are facilitating an unprecedented rate of
discovery of novel insights into the relationship between human genetic variation and …

Ethical principles guiding public health and genomic medicine are often at odds: whereas
public health practice adopts collectivist principles that emphasize population-based …

In the evaluation of genomic high-throughput technologies, the idea of “utility” plays an
important role. The “clinical utility” of genomic data refers to the improvement of healthcare …

The emerging need for family-centric initiatives for obtaining consent in personal genome
research | Genome Medicine Skip to main content SpringerLink Account Menu Find a journal …

Genomic medicine—an aspirational term 10 years ago—is gaining momentum across the
entire clinical continuum from risk assessment in healthy individuals to genome-guided …

Although still in the early stages of development, the advent of fast, high-output, and cost-
effective next-generation DNA sequencing technology is moving precision medicine into …