Ceramides are a class of sphingolipids that are abundant in cell membranes. They are
important structural components of the membrane but can also act as second messengers in …

Ceramides are sphingolipids and integral components of the eukaryotic cell membrane.
Apart from providing structural integrity, ceramides have also been shown to act as second …

Ceramide, the precursor of all complex sphingolipids, is a potent signaling molecule that
mediates key events of cellular pathophysiology. In the nervous system, the sphingolipid …

Ceramides are involved in a variety of cellular processes and in disease. Their biological
functions are thought to depend on ceramides' unique biophysical properties, which …

Ceramides are a class of sphingolipids which are implicated in skin disorders, obesity, and
other metabolic diseases. As a class with pleiotropic effects, recent efforts have centred on …

In the last 30 years, ceramides have been found to mediate a myriad of biological
processes. Ceramides have been recognized as bioactive molecules and their metabolizing …

Intensive research over the past 2 decades has implicated ceramide in the regulation of
several cell responses. However, emerging evidence points to dramatic complexities in …

Ceramide has been suggested to participate in the neuronal cell death that leads to
Alzheimer's disease (AD), but its role is not yet well-understood. We compared the levels of …

Background Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's
disease dementia (PDD), and frontotemporal lobar dementia (FTLD) are characterized by …

Accumulating evidences indicate that ceramide is closely involved in apoptotic cell death in
neurodegenerative disorders and aging. We examined ceramide levels in the cerebrospinal …