Somatostatin (SST) is a small peptide that exerts inhibitory effects on a wide range of
neuroendocrine cells. Due to the fact that somatostatin regulates cell growth and hormone …

In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased.
Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases …

Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …

Introduction• The somatostatin receptor as a GPCR• Anti‐tumour effects of somatostatin•
Post‐receptor signalling pathways‐Phosphotyrosine phosphatases and their action on …

Neuroendocrine neoplasms (NENs) are heterogeneous neoplasms which arise from
neuroendocrine cells that are distributed widely throughout the body. Although …

Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …

Endogenous somatostatin shows anti-secretory effects in both physiological and
pathological settings, as well as inhibitory activity on cell growth. Since somatostatin is not …

Introduction: Somatostatin analogs (SSAs) are used as part of standard treatment for
advanced neuroendocrine tumors (NETs). The mechanisms behind the antiproliferative …

• Conclusions 2586 reconsidered, it is also understandable that not always will these two
components go hand in hand in every tumour treated. There are GH-secreting pituitary …

Purpose Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) comprise a
heterogeneous group of malignancies often presenting with metastasis at diagnosis and …