[HTML][HTML] Current practice in the measurement and interpretation of intervention adherence in randomised controlled trials: A systematic review
Background Ideally all participants in a randomised controlled trial (RCT) should fully
receive their allocated intervention; however, this rarely occurs in practice. Intervention …
receive their allocated intervention; however, this rarely occurs in practice. Intervention …
Adherence reporting in randomized controlled trials
Background Treatment adherence may influence the therapeutic effect that is observed in a
randomized controlled trial (RCT). Adherence may also be an indicator of research quality …
randomized controlled trial (RCT). Adherence may also be an indicator of research quality …
[HTML][HTML] Nonadherence to treatment protocol in published randomised controlled trials: a review
S Dodd, IR White, P Williamson - Trials, 2012 - Springer
This review aimed to ascertain the extent to which nonadherence to treatment protocol is
reported and addressed in a cohort of published analyses of randomised controlled trials …
reported and addressed in a cohort of published analyses of randomised controlled trials …
The impacts of undetected nonadherence in phase II, III and post‐marketing clinical trials: An overview
E Le Flohic, B Vrijens… - British Journal of Clinical …, 2024 - Wiley Online Library
Aims This research aims to provide an overview of the consequences of undiagnosed
nonadherence (noninitiation, suboptimal implementation, nonpersistence) in randomized …
nonadherence (noninitiation, suboptimal implementation, nonpersistence) in randomized …
Key considerations for choosing a statistical method to deal with incomplete treatment adherence in pragmatic trials
MB Hossain, ME Karim - Pharmaceutical Statistics, 2023 - Wiley Online Library
Pragmatic trials offer practical means of obtaining real‐world evidence to help improve
decision‐making in comparative effectiveness settings. Unfortunately, incomplete …
decision‐making in comparative effectiveness settings. Unfortunately, incomplete …
Guideline adherence in physical therapy: a systematic review
AGJ Kolman - 2012 - studenttheses.uu.nl
Background: The development and use of evidence based clinical practice guidelines is
widely advocated. Adherence with guidelines seems however to be moderate. To date no …
widely advocated. Adherence with guidelines seems however to be moderate. To date no …
[HTML][HTML] An observational study on the adherence to study registrations in German interventional and observational studies from various fields
C Thiele, G Hirschfeld - PeerJ, 2023 - peerj.com
Background The registration of studies, especially in the case of clinical trials, is required by
the declaration of Helsinki and the policies of various scientific journals. However, numerous …
the declaration of Helsinki and the policies of various scientific journals. However, numerous …
[HTML][HTML] The reporting of treatment nonadherence and its associated impact on economic evaluations conducted alongside randomized trials: a systematic review
SL Brilleman, C Metcalfe, TJ Peters, W Hollingworth - Value in Health, 2016 - Elsevier
Objectives To review trial-based economic evaluations, identifying 1) the proportion
reporting adherence, 2) methods for assigning intervention costs according to adherence, 3) …
reporting adherence, 2) methods for assigning intervention costs according to adherence, 3) …
[HTML][HTML] Quality of intervention delivery in a cluster randomised controlled trial: a qualitative observational study with lessons for fidelity
K James, A Quirk, S Patterson, G Brennan, D Stewart - Trials, 2017 - Springer
Background Understanding intervention fidelity is an essential part of the evaluation of
complex interventions because fidelity not only affects the validity of trial findings, but also …
complex interventions because fidelity not only affects the validity of trial findings, but also …
How the EMERGE guideline on medication adherence can improve the quality of clinical trials
L Eliasson, S Clifford, A Mulick… - British journal of …, 2020 - Wiley Online Library
Medication adherence in drug trials is suboptimal, affecting the quality of these studies and
adding significant costs. Nonadherence in this setting can lead to null findings, unduly large …
adding significant costs. Nonadherence in this setting can lead to null findings, unduly large …